Shuji Kochi

Gastric-Type Adenomas of the Nonampullary Duodenum

Hidetaka Yamamoto, Shinichiro Kawatoko, Yumi Oshiro, Koichi Kurahara et autres

Nonampullary duodenal neoplasms of gastric phenotype include pyloric gland adenoma, foveolar-type adenoma, and duodenal neoplasm of uncertain malignant potential. In addition, previously undesignated epithelial tumors have been observed in the duodenum. Their clinicopathological and molecular characteristics, as well as their pathologic classification, …

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Tropical sprue differentiated from celiac disease: First case report in Japan

Shuji Kochi, Yumi Oshiro, Kazufumi Dohmen

A 66-year-old Japanese woman living in Indonesia for 3 years visited our hospital because of 13-years' duration of stinking steatorrhea, weight loss, and abdominal distention. Her symptoms occurred in Indonesia. She did not take any regular medications. Abnormal laboratory tests were the …

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Measurement of prostaglandin metabolites is useful in diagnosis of small bowel ulcerations

Yuichi Matsuno, Junji Umeno, Motohiro Esaki, Yoichiro Hirakawa et autres

BACKGROUND: gene (CEAS). Crohn's disease (CD) is a major differential diagnosis of CEAS, because these diseases share some clinical features. Therefore, there is a need to develop a convenient screening test to distinguish CEAS from CD. AIM: To examine whether prostaglandin E …

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Clinical usefulness of magnifying colonoscopy for the diagnosis of ulcerative colitis‐associated neoplasia

Keisuke Kawasaki, Shotaro Nakamura, Motohiro Esaki, Koichi Kurahara et autres

Background and Aim The aim of this investigation was to evaluate the efficacy of Japanese magnifying colonoscopic classifications for ulcerative colitis‐associated neoplasia (UCAN). Methods We reviewed the colonoscopy records from 2011 to 2018 at our institutions and identified cases of endoscopically or …

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Capsule endoscopy findings for the diagnosis of Crohn’s disease: a nationwide case–control study

Motohiro Esaki, Takayuki Matsumoto, Naoki Ohmiya, Ema Washio et autres

BACKGROUND: Capsule endoscopy can be used to identify the early stage of small bowel Crohn's disease (CD). We evaluated significant small bowel capsule endoscopy (SBCE) findings that can lead to early diagnosis of CD. METHODS: We retrospectively accumulated clinical and SBCE data …

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Secondary gastrointestinal amyloid A amyloidosis possibly caused by hidradenitis suppurativa

Shuji Kochi, Motohiro Esaki, Koichi Kurahara

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P129 USEFULNESS OF PROSTAGLANDIN E-MAJOR URINARY METABOLITE MEASUREMENT FOR THE DIFFERENTIATION BETWEEN CHRONIC ENTEROPATHY ASSOCIATED WITH SLCO2A1 GENE (CEAS) AND CROHN’S DISEASE

Yuichi Matsuno, Junji Umeno, Yuta Fuyuno, Yasuharu Okamoto et autres

Chronic enteropathy associated with SLCO2A1 gene (CEAS) is a rare intractable disease characterized by persistent anemia and hypoproteinemia due to multiple small intestinal ulcers. Recently, we identified that the disease is caused by loss-of-function mutations of SLCO2A1 gene, encoding a prostaglandin transporter. …

Clinical features of chronic enteropathy associated with SLCO2A1 gene: a new entity clinically distinct from Crohn’s disease

Junji Umeno, Motohiro Esaki, Atsushi Hirano, Yuta Fuyuno et autres

BACKGROUND: Chronic enteropathy associated with SLCO2A1 gene (CEAS) is a hereditary disease caused by mutations in the SLCO2A1 gene and characterized by multiple small intestinal ulcers of nonspecific histology. SLCO2A1 is also a causal gene of primary hypertrophic osteoarthropathy (PHO). However, little …

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P129 USEFULNESS OF PROSTAGLANDIN E-MAJOR URINARY METABOLITE MEASUREMENT FOR THE DIFFERENTIATION BETWEEN CHRONIC ENTEROPATHY ASSOCIATED WITH SLCO2A1 GENE (CEAS) AND CROHN’S DISEASE

Yuichi Matsuno, Junji Umeno, Yuta Fuyuno, Yasuharu Okamoto et autres

Real life results in using 5-ASA for maintaining mild to moderate UC patients in Japan, a multi-center study, OPTIMUM Study

Masakazu Nagahori, Shuji Kochi, Hiroyuki Hanai, Takayuki Yamamoto et autres

BACKGROUND: Efficacy of maintenance therapy in ulcerative colitis (UC) in the remission stage has been reported to depend on release profile or dosing regimen of oral 5-aminosalicylic acid (5-ASA) products used. Aim of this study is to investigate real life results in …

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Additional file 2: of Real life results in using 5-ASA for maintaining mild to moderate UC patients in Japan, a multi-center study, OPTIMUM Study

Masakazu Nagahori, Shuji Kochi, Hiroyuki Hanai, Takayuki Yamamoto et autres

The name of committee. (XLS 50 kb)

Additional file 1: of Real life results in using 5-ASA for maintaining mild to moderate UC patients in Japan, a multi-center study, OPTIMUM Study

Masakazu Nagahori, Shuji Kochi, Hiroyuki Hanai, Takayuki Yamamoto et autres

A questionnaire on adherence to medication of the oral 5-ASA products. (DOC 47 kb)