K. Tomiyama

Coexistence Tumor of Craniopharyngioma and Pituitary Neuroendocrine Tumor: A Case Report and Literature Review

Yohei Nounaka, Fumihiro Matano, K Isayama, K. Tomiyama et autres

Acromegaly most commonly results from excess growth hormone (GH) produced by pituitary neuroendocrine tumors (PitNETs). Craniopharyngioma (CP) is an uncommon suprasellar tumor characterized by cystic change and calcification. The true coexistence of PitNET and CP is rare and poses diagnostic and operative …

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810 A novel KITLG mutation detected only in the lesion of linear and whorled nevoid hypermelanosis

Satoru Shinkuma, Rei Yokoyama, Ryota Hayashi, Hong-Hanh Nguyen et autres

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Experimental Autoimmune Labyrinthitis Induced by Cell-mediated Immune Reaction

K. Tomiyama

This study was designed to establish an experimental cell-mediated autoimmune labyrinthitis model in C57BL/6 mice, which could exhibit high reproducibility and be adopted for precise immunological analysis. Inner ear antigen (IEA) was prepared from bovine membranous labyrinth. Following pretreatment with cyclophosphamide (CP) …

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Phenotypic and functional modulation of T cellsin vivoby extrathymic T cells when T cells with MHC class II disparity were injected into athymic nude mice

K. Tomiyama, Haruki Watanabe, Shinichiro Seki, Masaaki Ito et autres

TCRhigh cells are generated by the mainstream of T cell differentiation in the thymus, whereas TCRint cells (or NK1.1+ T cells) are generated extrathymically in the liver and by an alternative intrathymic pathway. It is still unknown how these T cell populations …

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094 Possible involvement of dendritic epidermal T cells in the resistance to cutaneous GVHD in euthymic mice

K. Tomiyama, Masahiro Minagawa, Ayumu Ito, Kazuhiro Kawai et autres

Induction of GVHD with cutaneous lesion in athymic nude mice and contribution of extrathymic T cells to the pathogenesis

K. Tomiyama, Katsuyuki Kawai, Mikako Ito

PREFERENTIAL DISTRIBUTION OF Vβ8.2+ T CELLS IN THE RAT CENTRAL NERVOUS SYSTEM WITH MYELIN BASIC PROTEIN-AUTOIMMUNE ENCEPHALOMYELITIS

Y Matsumoto, M Tsuchida, H. Hanawn, Hiroyuki Hirahara et autres