Woo Jean Kim

Vasohibin-1 rescues erectile function through up-regulation of angiogenic factors in the diabetic mice

Kang‐Moon Song, Woo Jean Kim, Min Ji Choi, Ki‐Dong Kwon et autres

Neovascularization of the erectile tissue emerges as a beneficial curative approach to treat erectile dysfunction (ED). Here we for the first time report the unexpected role of vasohibin-1 (VASH1), mainly known as an anti-angiogenic factor, in restoring erectile function in diabetic mice. …

kr, jp (code pays fourni par la source)

Isolinderalactone Induces Cell Death via Mitochondrial Superoxide- and STAT3-Mediated Pathways in Human Ovarian Cancer Cells

Rajina Shakya, Woo Jean Kim, Jung‐Hyun Shim, Kyung‐Soo Chun et autres

The mortality rate of ovarian cancer (OC) worldwide increases with age. OC is an often fatal cancer with a curative rate of only 20–30%, as symptoms often appear after disease progression. Studies have reported that isolinderalactone (ILL), a furanosesquiterpene derivative extracted from …

kr (code pays fourni par la source)

Isolinderalactone suppresses human glioblastoma growth and angiogenic activity in 3D microfluidic chip and in vivo mouse models

Jung Hwa Park, Min Jae Kim, Woo Jean Kim, Ki‐Dong Kwon et autres

kr (code pays fourni par la source)

The MicroRNA-92a/Sp1/MyoD Axis Regulates Hypoxic Stimulation of Myogenic Lineage Differentiation in Mouse Embryonic Stem Cells

Seo Yeon Lee, Jimin Yang, Jung Hwa Park, Hwa Kyoung Shin et autres

Hypoxic microenvironments exist in developing embryonic tissues and determine stem cell fate. We previously demonstrated that hypoxic priming plays roles in lineage commitment of embryonic stem cells. In the present study, we found that hypoxia-primed embryoid bodies (Hyp-EBs) efficiently differentiate into the …

kr, ca (code pays fourni par la source)

Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model

Ji Young Hwang, Jung Hwa Park, Min Jae Kim, Woo Jean Kim et autres

kr (code pays fourni par la source)

Cordycepin inhibits lipopolysaccharide-induced cell migration and invasion in human colorectal carcinoma HCT-116 cells through down-regulation of prostaglandin E2receptor EP4

Jin-Woo Jeong, Cheol Park, Hee‐Jae Cha, Su Hyun Hong et autres

Prostaglandin E2 (PGE2), a major product of cyclooxygenase-2 (COX-2), plays an important role in the carcinogenesis of many solid tumors, including colorectal cancer. Because PGE2 functions by signaling through PGE2 receptors (EPs), which regulate tumor cell growth, invasion, and migration, there has …

kr (code pays fourni par la source)

AB035. Vasohibin-1 as a potential therapeutic target for erectile dysfunction

Kang‐Moon Song, Woo Jean Kim, Guo Nan Yin, Ji‐Kan Ryu et autres

Induction of neovascularization is a promising strategy to treat erectile dysfunction (ED). Here we for the first time report the unexpected role of vasohibin-1, which is previously defined as an anti-angiogenic factor, in the restoration of erectile function by enhancing cavernous (penile) …

kr (code pays fourni par la source)

The aqueous extract from Artemisia capillaris inhibits acute gastric mucosal injury by inhibition of ROS and NF-kB

Dahee Yeo, Su Jung Hwang, Woo Jean Kim, Hyun‐Joo Youn et autres

kr (code pays fourni par la source)

MP89-01 VASOHIBIN-1 IS A NOVEL THERAPEUTIC TARGET FOR DIABETIC ERECTILE DYSFUNCTION IN MICE

Woo Jean Kim, Kang‐Moon Song, Jin‐Mi Park, Anita Limanjaya et autres

You have accessJournal of UrologySexual Function/Dysfunction: Basic Research & Pathophysiology II1 Apr 2016MP89-01 VASOHIBIN-1 IS A NOVEL THERAPEUTIC TARGET FOR DIABETIC ERECTILE DYSFUNCTION IN MICE Woo Jean Kim, Kang-Moon Song, Jin-Mi Park, Anita Limanjaya, Kalyan Ghatak, Nguyen Nhat Minh, Soo-Hwan Park, Won-Hee …

kr (code pays fourni par la source)

Hypoxia-induced fibroblast growth factor 11 stimulates capillary-like endothelial tube formation

Jimin Yang, Woo Jean Kim, Hyoung Oh Jun, Eun Ju Lee et autres

Low oxygen or hypoxia can be observed in the central region of solid tumors. Hypoxia is a strong stimulus for new blood vessel formation or angiogenesis, which is essential for tumor growth and progression. Fibroblast growth factor 11 (FGF11) is an intracellular …

kr (code pays fourni par la source)

The pericyte as a cellular regulator of penile erection and a novel therapeutic target for erectile dysfunction

Guo Nan Yin, Nando Dulal Das, Min Ji Choi, Kang‐Moon Song et autres

Pericytes are known to play critical roles in vascular development and homeostasis. However, the distribution of cavernous pericytes and their roles in penile erection is unclear. Herein we report that the pericytes are abundantly distributed in microvessels of the subtunical area and …

kr (code pays fourni par la source)

MP52-03 THE PERICYTES AS A CELLULAR REGULATOR OF PENILE ERECTION AND A NOVEL THERAPEUTIC TARGET FOR ERECTILE DYSFUNCTION

Guo Nan Yin, Nando Dulal Das, Min Ji Choi, Kang‐Moon Song et autres

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Basic Research I1 Apr 2015MP52-03 THE PERICYTES AS A CELLULAR REGULATOR OF PENILE ERECTION AND A NOVEL THERAPEUTIC TARGET FOR ERECTILE DYSFUNCTION Guo Nan Yin, Nando Dulal Das, Min Ji Choi, Kang-Moon Song, Mi-Hye Kwon, Jiyeon …

kr (code pays fourni par la source)