J.A. Bell

Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using in silico Enabled Drug Discovery Platform

Hideyuki Igawa, Zef Konst, Éric Therrien, Mee Shelley et autres

Despite the success of first, second and third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in treatment of non-small cell lung cancer (NSCLC) with classical EGFR mutations (L858R or Exon 19 deletions), disease progression often occurs due to the …

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Improved early clinical development through human microdosing studies

Ian R. Wilding, J.A. Bell

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Selective blockade of spinal reflexes by ω-conotoxin in the isolated spinal cord of the neonatal rat

J.A. Bell

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Twenty years on: a review of the current practice of drug metabolism and pharmacokinetic studies in the pharmaceutical industry

J.A. Bell, Michael H. Tarbit

Twenty years on: a review of the current practice of drug metabolism and pharmacokinetic studies in the pharmaceutical industry

Clonidine attenuates increased brain glucose metabolism during naloxone-precipitated morphine withdrawal

Alane S. Kimes, J.A. Bell, Edythe D. London

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Partial agonists of the morphine type: Facilitative effects on electrophysiologically recorded C-fiber reflexes in the cat

J.A. Bell

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Electrophysiologically recorded C-fiber reflexes in intact and acute decerebrate-spinal cats: Absence of nalckone facilitation in intact cats

J.A. Bell, L. G. Sharpe, Wallace B. Pickworth

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Prevent shivering during hypothermia treatment.

Arti Barnes, J.A. Bell

Inhibitory effects of dorsal horn and excitant effects of ventral horn intraspinal microinjections of norepinephrine and serotonin in the cat

J.A. Bell, Teruhiko Matsumiya

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THE MODE OF ACTION OF LSD-LIKE HALLUCINOGENS AND THEIR IDENTIFICATION

William R. Martin, D. Bruce Vaupel, Jewell W. Sloan, J.A. Bell et autres

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The absence of an effect of L-tryptophan on the C-fiber reflex in the chronic spinal cat

J.A. Bell, William R. Martin

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Responses of the flexor reflex to LSD, tryptamine, 5-hydroxytryptophan, methoxamine, and d-amphetamine in acute and chronic spinal rats

M Nozaki, J.A. Bell, D. Bruce Vaupel, William R. Martin

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