G.V. Sherbet

Embryonic and Tumour Cell Interactions

M.S. Lakshmi, G.V. Sherbet

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S100A4 (S100 Calcium Binding Protein A4)

G.V. Sherbet

S100A4 (S100 calcium binding protein A4)

G.V. Sherbet

Review on S100A4 (S100 calcium binding protein A4), with data on DNA, on the protein encoded, and where the gene is implicated.

Introduction

G.V. Sherbet

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The Surface Properties of Some Human Intracranial Tumour Cell Lines in Relation to Their Malignancy

G.V. Sherbet, M.S. Lakshmi

The electronegativity of the surfaces of 8 human astrocytoma lines, 3 lines of meningioma, and one line of normal foetal brain cells, has been investigated using the isoelectric equilibrium method. The tumour cultures were initiated from human biopsy material and the foetal …

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Breast cancer and therapeutic deployment of growth factor receptors.

G.V. Sherbet

Membrane Surface Properties of Normal and Malignant Cells: Partition in Aqueous Two-Polymer Phase Systems

G.V. Sherbet, M.S. Lakshmi

The partition of normal and malignantly transformed fibroblast lines and cell lines initiated from malignant human astrocytomas and a benign ganglioneuroma has been examined in aqueous dextran-polyethylene glycol phase system containing phosphate buffer with a low phosphate/sodium chloride ratio. The malignant astrocytomas …

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The Cell Surface Sulphydryl Content of Metastatic Variants of B16 Murine Melanoma

G.V. Sherbet

The cell surface sulphydryl content of three metastatic variants of the B16 murine melanoma has been determined using isoelectric equilibrium techniques. The F1 variant, which has no ability for natural metastasis, and the F10 variant with moderate metastatic ability appeared to have …

The Role of Cell Surface Proteins in the Induction of Histogenetic Differentiative Responses by Some Human Breast Tumours and Hamster Tumours Implanted into Chick Embryos

M.S. Lakshmi, A.L. Latner, G.V. Sherbet

Cells of human breast tumours and fibrocystic hyperplasia grown in culture, and three hamster tumours were implanted between the cell layers of 18-hour-old chick blastoderm. Their ability to induce histogenetic responses in the ectodermal and endodermal embryonic tissues was investigated. The surface …

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Membrane Fluidity and Cancer Metastasis

G.V. Sherbet

The membrane fluidity of murine B16 melanoma and L5178 lymphoma variants is examined in relation to their metastatic potential. A higher lateral mobility of membrane proteins in metastasis is indicated by lectin receptor-mediated agglutination studies, but these do not constitute incontrovertible evidence …

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A Comparison of the Electrokinetic Properties of Metastasizing and Non-Metastasizing Forms of a Hamster Lymphosarcoma

G. A. Turner, G.V. Sherbet, M Wildridge

Metastasizing (ML) and non-metastasizing (NML) forms of a hamster lymphosarcoma were investigated for possible differences in the cell surface properties using isoelectric equilibrium analysis and cytopherometry. ML cells were found to have a higher isoelectric point (pI) and therefore a lower net …

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Detection of Receptor-Mediated Membrane Effects of Dexamethasone in B16 Murine Melanoma Cell Lines by Cell Partitioning in Aqueous Two-Polymer Systems

G. P. risely, G.V. Sherbet

Four metastatic variant sublines of the B16 murine melanoma were assayed for glucocorticoid receptors and examined for effects of dexamethasone on surface charge-related partition behaviour in aqueous two-polymer systems, expression of membrane external proteins, and adhesion to growth substratum. BL6 and F10 …

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