Yoshio Oka

A Phase II Trial of Trastuzumab Combined With Irinotecan in Patients With Advanced HER2-positive Chemotherapy-refractory Gastric Cancer (OGSG1203 HERBIS-5): Final Results

Junji Kawada, Daisuke Sakai, Yutaka Kimura, Motohiro Hirao et autres

BACKGROUND/AIM: Irinotecan is a key drug for patients with advanced gastric cancer. We assessed the efficacy and safety of combination chemotherapy with trastuzumab and irinotecan in patients with advanced human epidermal growth factor receptor type 2 (HER2)-positive chemotherapy-refractory gastric cancer. PATIENTS AND …

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Salvage-line of Capecitabine Plus Oxaliplatin Therapy (XELOX) for Patients With Inoperable/Advanced Gastric Cancer Resistant/Intolerant to Cisplatin (OGSG1403)

Naotoshi Sugimoto, Junji Kawada, Yoshio Oka, Kohei Murakami et autres

Background/Aim: No prospective study has evaluated salvage chemotherapy with capecitabine plus oxaliplatin (XELOX) in patients with gastric cancer who are resistant to or intolerant of cisplatin. Patients and Methods: This multicenter, open-label, single-arm, phase II study was conducted at six centers in …

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[An Experience of S-1-Induced Rhabdomyolysis and Refractory Enteritis during Postoperative Adjuvant Chemotherapy for Gastric Cancer].

Kei Yamamoto, Yoshio Oka, Shuhei Murao, Masaya Higashiguchi et autres

Fluoropyrimidines are one of the key drugs in cancer chemotherapy, but rare adverse events are difficult to diagnose and treat. Here we report a case who developed the relatively rare adverse events of rhabdomyolysis and refractory enteritis during S-1-based chemotherapy for gastric …

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[A Case of Surgery for Skin Metastasis of Papillary Thyroid Carcinoma in a Very Elderly Patient to Improve the Quality of Life].

Emi Takeda, Yasuhiro Toyoda, H. Yamamoto, Itsuko Nakamichi et autres

The patient was a 100-year-old woman who underwent right lobe thyroidectomy for papillary thyroid cancer in another hospital around 1990. She developed local recurrence in 2010 and underwent anterior tracheal local recurrence resection in May 2017. Subsequently, metastases were confirmed in the …

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[An Experience of Multidisciplinary Treatment for Advanced Esophageal Cancer with Tumor Perforation during Preoperative Chemotherapy].

Kei Yamamoto, Makoto Yamasaki, Takafumi Hirao, Yoshio Oka et autres

Perforation of esophageal cancer is one of the fatal oncologic emergencies, and a prompt and accurate treatment strategy is required. Here, we report a case of advanced esophageal cancer that had perforated during preoperative chemotherapy and was successfully resected with multidisciplinary treatment. …

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[A Case of Right Hemicolectomy for Inflammatory Myofibroblastic Tumor Arising in the Right Transverse Colon].

Takashi Takeda, Kenta Takahashi, Katsuki Danno, Itsuko Nakamichi et autres

The patient was a 21-year-old male. He presented with right lower abdominal pain and showed tenderness in the same area. An abdominal contrast-enhanced CT examination revealed a 45 mm tumor that continuously stained in the right transverse colon. The patient presented with …

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Comparison of Clinical Outcomes Between Laparoscopic and Open Extensive Resection for Complicated Appendicitis: Retrospective Observational Study

Hiroshi Takeyama, Kimimasa Ikeda, Satoshi Shinomiya, Takahiko Nishigaki et autres

BACKGROUND: The feasibility and safety of laparoscopic extensive resection (ER) for complicated appendicitis (CA) has not been clarified. We assessed the feasibility of laparoscopic ER versus open ER for CA. METHODS: We retrospectively enrolled consecutive 983 patients who underwent emergency surgery for …

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[A Case of Recurrent Hepatocellular Carcinoma Successfully Treated by Radiation Therapy].

Kenta Takahashi, Masafumi Yamashita, Keishi Sugimoto, Sachi Kawagishi et autres

We report a case of recurrent hepatocellular carcinoma(HCC)successfully treated by radiation therapy. A 79-year-old woman was diagnosed with HCC and underwent liver resection. Seven months after resection, CT and MRI detected a new HCC, and she had a surgery again. One year …

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Survival analysis of a prospective multicenter observational study on surgical palliation among patients receiving treatment for malignant gastric outlet obstruction caused by incurable advanced gastric cancer

Masanori Terashima, Kazumasa Fujitani, Masahiko Ando, Kentaro Sakamaki et autres

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Primary results of multicenter phase II study of neoadjuvant chemotherapy with S-1 and oxaliplatin for locally advanced gastric cancer (Neo G-SOX PII)

Akira Miki, Hironaga Satake, Takanori Watanabe, Norimitsu Tanaka et autres

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[Experience of Perioperative Status for Super Elderly Colorectal Patients in Our Facility].

Shinichi Yoshioka, Yoshio Oka, Satoshi Kawanaka, Kaoru Okada et autres

We examined the perioperative situation according to estimation of physiologic ability and surgical stress(E-PASS)score of 35 colon cancer patients aged 85 years or older who underwent operation in our facility. The incidence of Grade 2 and Grade 3 complications according to Clavien-Dindo …

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A survival analysis of a prospective multicenter observational study of surgical palliation in patients treated for malignant gastric outlet obstruction caused by incurable advanced gastric cancer.

Masanori Terashima, Kazumasa Fujitani, Masahiko Ando, Kentaro Sakamaki et autres

113 Background: We previously reported that surgical palliation maintained patients’ quality of life (QOL) while improving the solid food intake with an acceptable surgical safety in patients with malignant gastric outlet obstruction (GOO) caused by advanced gastric cancer. To elucidate the impact …

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