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Profil bibliographique

T. Gauthier

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

9Publications signalées
183Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Liver Disease Diagnosis and TreatmentLiver physiology and pathologyLiver Diseases and ImmunityHepatocellular Carcinoma Treatment and PrognosisHepatitis C virus research

Les publications récentes

2025 article OpenAlex

Identification of senescence markers on cultured human corneal endothelial cells

Tomy Sagnial, Zhiguo Hé, T. Gauthier, Inès Aouimeur et autres

Aims/Purpose: Corneal transplantation is currently the most frequent type of transplantation globally. However, a chronic shortage of donor corneas makes traditional methods unsustainable. Alternatives such as bio‐engineered grafts or direct injection of corneal endothelial cells (CECs) into the patient's eye require the …

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0 citations Acta Ophthalmologica
1997 article OpenAlex

Effect of quinolone antibiotics on hepatic growth and protein synthesis following partial hepatectomy in rats

G Y Minuk, Nimar Assy, LX DING, T. Gauthier et autres

Quinolone antibiotics inhibit eukaryotic as well as prokaryotic cell growth and protein synthesis. To determine whether these properties adversely affect hepatic growth and recovery following surgical resection, five groups of healthy, adult male rats (n = 7-8/group) were treated for 10 days …

ca (code pays fourni par la source)

5 citations Journal of Gastroenterology and Hepatology
1996 article OpenAlex

A comparative trial of recombinant interferon alpha 2A versus alpha 2 beta on myelosuppression in healthy adult volunteers.

Stephen Wong, Kelly Kaita, T. Gauthier, Surai Jones et autres

BACKGROUND/AIMS: Recombinant interferon (r-IFN) is an antiviral agent used to treat patients with chronic viral hepatitis patients. Unfortunately, the use is often limited due to its myelosuppressive properties. Currently, there are two forms of r-IFN commercially available: r-IFN alpha-2a and rIFN alpha-2b. …

ca (code pays fourni par la source)

20 citations PubMed
1996 article OpenAlex

Changes in liver membrane potentials after partial hepatectomy in rats

X K Zhang, T. Gauthier, Frank J. Burczynski, G Q Wang et autres

Changes in potential differences (PD) across hepatocyte membranes after partial hepatectomy may play an important role in hepatic homeostatic mechanisms and regenerative activity. To date, few studies have attempted to describe the extent and duration of such changes. In the present study, …

ca (code pays fourni par la source)

21 citations Hepatology
1995 article OpenAlex

Effect of exogenous γ-aminobutyric acid (GABA) on hepatic insulin-like growth factor I (IGF-I) and IGF-I binding protein (IGFBP-I) mRNA abundance following partial hepatectomy in rats

Gerald Yosel Minuk, K. D. E. Kaita, T. Gauthier, Thomas C. Dembinski et autres

Insulin-like growth factor I (IGF-I) and IGF-I binding protein (IGFBP-I) are highly expressed in the liver and may play an important role in enhancing hepatic regeneration following partial hepatectomy in rats. Since hepatic levels of these growth factors are influenced by pituitary …

ca (code pays fourni par la source)

5 citations Canadian Journal of Physiology and Pharmacology
1993 article OpenAlex

Cerebral metabolic and histological effects of thioacetamide-induced liver failure

James Peeling, Leena N. Shoemaker, T. Gauthier, Abraham Benarroch et autres

Acute liver failure was induced in rats by successive administrations of thioacetamide over 3 days. At progressing stages of hepatic encephalopathy (HE), brains were fixed with microwave irradiation for analysis of metabolite levels or with formaldehyde for histopathological analysis. Metabolite levels were …

ca (code pays fourni par la source)

70 citations American Journal of Physiology-Gastrointestinal and Liver Physiology
1992 article OpenAlex

A pilot study of steroid withdrawal followed by oral acyclovir in the treatment of chronic type B hepatitis.

GY Minuk, German Gb, C N Bernstein, A Benarroch et autres

Ten patients with chronic type B hepatitis were treated for four weeks with a rapidly tapered dose of oral prednisone (initial dose, 40 mg/d) followed by two weeks of no therapy followed by four weeks of oral acyclovir (600 mg/d). Liver biochemistry, …

ca (code pays fourni par la source)

10 citations PubMed
1991 article OpenAlex

The effect of long-term, voluntary ethanol consumption on hepatic regeneration in rats

Gerald Yosel Minuk, Gary E. Rockman, T. Gauthier, Lynn E. Markert et autres

Previous studies have reported conflicting results regarding the effect of ethanol on hepatic regeneration. The purpose of the present study was to determine whether long-term, voluntary consumption of ethanol, within the range reported in humans, has an effect on hepatic regenerative activity …

ca (code pays fourni par la source)

7 citations Canadian Journal of Physiology and Pharmacology

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