Michael W. Schlegel

Late regulation of immune genes and microRNAs in circulating leukocytes in a pig model of influenza A (H1N2) infection

Louise Brogaard, Peter M. H. Heegaard, Lars Erik Larsen, Shila Mortensen et autres

MicroRNAs (miRNAs) are a class of short regulatory RNA molecules which are implicated in modulating gene expression. Levels of circulating, cell-associated miRNAs in response to influenza A virus (IAV) infection has received limited attention so far. To further understand the temporal dynamics …

dk, de (code pays fourni par la source)

Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013

Simon J. Watson, Pinky Langat, Scott M. Reid, Tommy Tsan‐Yuk Lam et autres

UNLABELLED: The emergence in humans of the A(H1N1)pdm09 influenza virus, a complex reassortant virus of swine origin, highlighted the importance of worldwide influenza virus surveillance in swine. To date, large-scale surveillance studies have been reported for southern China and North America, but …

gb, be, it, dk, pl, de, fi, hu, nl, us (code pays fourni par la source)

MicroRNA regulation of TLRs in a post-influenza animal model

Louise Brogaard, Peter M. H. Heegaard, Lars Erik Larsen, Ralf Dürrwald et autres

Introduction Substantial morbidity and mortality is caused by secondary bacterial infections occurring in individuals after influenza A virus (IAV) infection. Results from studies in mice suggest that this may in part be due to a lack of responsiveness to Toll-like receptor (TLR) …

dk, de (code pays fourni par la source)

Just-In-Time eTraining Applied To Emergency Medical Services

Francisco Jose Vico-Vela, Vicente Sánchez Canteli, Daniel Lobo Fernández, José David Fernández-Rodríguez et autres

While the applications of just-in-time training are more and more spread, the ubiquitous mobile technology has not found practical uses of this training strategy. As an original example of services for healthcare, we present in this work an application of eTraining that …

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Reassortants of the pandemic (H1N1) 2009 virus and establishment of a novel porcine H1N2 influenza virus, lineage in Germany

Jeannette Lange, Marco Groth, Michael W. Schlegel, Andi Krumbholz et autres

de (code pays fourni par la source)

Efficacy of Influenza Vaccination and Tamiflu® Treatment – Comparative Studies with Eurasian Swine Influenza Viruses in Pigs

Ralf Duerrwald, Michael W. Schlegel, Katja Bauer, Théophile Vissiennon et autres

Recent epidemiological developments demonstrated that gene segments of swine influenza A viruses can account for antigenic changes as well as reduced drug susceptibility of pandemic influenza A viruses. This raises questions about the efficacy of preventive measures against swine influenza A viruses. …

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Expression of innate immune genes, proteins and microRNAs in lung tissue of pigs infected experimentally with influenza virus (H1N2)

Kerstin Skovgaard, Susanna Cirera, Ditte Erika Leth Vasby, Agnieszka Podolska et autres

This study aimed at providing a better understanding of the involvement of innate immune factors, including miRNA, in the local host response to influenza virus infection. Twenty pigs were challenged by influenza A virus subtype H1N2. Expression of microRNA (miRNA), mRNA and …

dk, de (code pays fourni par la source)

Expression of innate immune genes, proteins and microRNAs in lung tissue and leukocytes of pigs infected with influenza virus

Kerstin Skovgaard, Susanna Cirera, Ditte Erika Leth Vasby, Agnieszka Podolska et autres

This study aimed at providing a better understanding of the involvement of innate immune factors including microRNA (miRNA) in the local and systemic host response to influenza virus infection. Twenty pigs were challenged by influenza A virus subtype H1N2. Expression of miRNA, …

dk, de (code pays fourni par la source)

IOD IN RHINOS—NUTRITION GROUP REPORT: REPORT FROM THE NUTRITION WORKING GROUP OF THE INTERNATIONAL WORKSHOP ON IRON OVERLOAD DISORDER IN BROWSING RHINOCEROS (FEBRUARY 2011)

Marcus Clauß, Ellen Sue Dierenfeld, Jesse Paul Goff, Kirk C. Klasing et autres

Iron overload disorder (IOD) has been identified in browser rhinoceros species (eg. black rhino, Diceros bicornis; Sumatran rhino, Dicerorhinus sumatrensis), although the mechanism by which IOD occurs in these species is unclear. It is known that browser rhino species are susceptible to …

us, ch (code pays fourni par la source)

Neuraminidase inhibitor susceptibility of swine influenza A viruses isolated in Germany between 1981 and 2008

Katja Bauer, Ralf Dürrwald, Michael W. Schlegel, Kathrin Pfarr et autres

de (code pays fourni par la source)

Swine Influenza A Vaccines, Pandemic (H1N1) 2009 Virus, and Cross-Reactivity

Ralf Dürrwald, Andi Krumbholz, Sigrid Baumgarte, Michael W. Schlegel et autres

Infl uenza surge planning is premised on a high incidence of illness among elderly persons, but if the current pattern of illness continues, healthcare facilities also should prepare to treat younger persons who may constitute the bulk of cases.Additionally, studies of persons …

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Neuraminidase Inhibitor Susceptibility of Swine Influenza A Viruses Isolated Between 1981and 2008 in Germany

Michaela Schmidtke, Katja Bauer, Dominik Topf, Heike Braun et autres

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