Sang Soo Cho

Imaging Monoacylglycerol Lipase A First-in-Human Positron Emission Tomography Study with [18F]MAGL-2102

Bertina Jebanesan, Lucas Narciso, Nikta Zarif Yussefian, Emily Murrell et autres

ca, us (code pays fourni par la source)

Assessment of noninvasive quantification of [18F]SynVesT-1 with simplified reference tissue model 2 in an adolescent and youth cohort

Carme Uribe, Lucas Narciso, Sang Soo Cho, Maia Zilberman et autres

PURPOSE: The suitability of the white matter centrum semiovale (CS) as a pseudo-reference region for simplified reference tissue model 2 (SRTM2) with [¹⁸F]SynVesT-1 PET has not been evaluated in youth cohorts. We aimed to assess noninvasive quantification methods and determine the minimum …

ca, us (code pays fourni par la source)

Reactive Astrocytes and Network Functional Connectivity Underlying Cognitive Symptoms in Schizophrenia: A Positron Emission Tomography and Functional Magnetic Resonance Imaging Study

Sunah Choi, Minah Kim, Sang Soo Cho, Harin Oh et autres

us, kr, ca (code pays fourni par la source)

In Vivo Reactive Astrocyte Imaging in Patients With Schizophrenia Using Fluorine 18–Labeled THK5351

Minah Kim, Woori Choi, Sunah Choi, Harin Oh et autres

Importance: In vivo imaging studies of reactive astrocytes are crucial for understanding the pathophysiology of schizophrenia because astrocytes play a critical role in glutamate imbalance and neuroinflammation. Objective: To investigate in vivo reactive astrocytes in patients with schizophrenia associated with positive symptoms …

kr (code pays fourni par la source)

Fronto-striato-thalamic circuit connectivity and neuromelanin in schizophrenia: an fMRI and neuromelanin-MRI study

Sunah Choi, Minah Kim, Taekwan Kim, Eun‐Jung Choi et autres

Changes in dopamine and fronto-striato-thalamic (FST) circuit functional connectivity are prominent in schizophrenia. Dopamine is thought to underlie connectivity changes, but experimental evidence for this hypothesis is lacking. Previous studies examined the association in some of the connections using positron emission tomography …

kr, pr (code pays fourni par la source)

Fronto-striato-thalamic circuit connectivity and neuromelanin in schizophrenia: an fMRI and neuromelanin-MRI study

Jun Soo Kwon, Sunah Choi, Minah Kim, Taekwan Kim et autres

Abstract Changes in dopamine and fronto-striato-thalamic (FST) circuit functional connectivity are prominent in schizophrenia. Dopamine is thought to underlie connectivity changes, but experimental evidence for this hypothesis is lacking. Previous studies examined the association in some of the connections using positron emission …

kr, Éthiopie (code pays fourni par la source)

Single‐Trajectory Multiple‐Target Deep Brain Stimulation for Parkinsonian Mobility and Cognition

Sanskriti Sasikumar, Mélanie Cohn, Irene E. Harmsen, Aaron Loh et autres

BACKGROUND: Deep brain stimulation (DBS) of the nucleus basalis of Meynert (NBM) is an emerging target to potentially treat cognitive dysfunction. OBJECTIVES: The aim of this study is to achieve feasibility and safety of globus pallidus pars interna (GPi) and NBM DBS …

ca, kr, br, au, us (code pays fourni par la source)

VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder

Mikaeel Valli, Sang Soo Cho, Carme Uribe, Mario Masellis et autres

Abstract REM sleep behaviour disorder (RBD) can be an early non-motor symptom of Parkinson’s disease (PD) with pathology involving mainly the pontine nuclei. Beyond the brainstem, it is unclear if RBD patients comorbid with PD have more affected striatal dopamine denervation compared …

ca, kr (code pays fourni par la source)

Combining transcranial brain stimulation and PET/SPECT molecular imaging

Sang Soo Cho, Antonio P. Strafella

Abstract Transcranial brain stimulation (TMS) was introduced in 1985 by Barker and his colleagues. Since then, further improvements in technology have allowed additional applications and new stimulation protocols. In the last decade, while the use of TMS has expanded enormously in basic …

ca (code pays fourni par la source)

VMAT2 Availability in Parkinson’s Disease with REM Sleep Behaviour Disorder

Mikaeel Valli, Sang Soo Cho, Carme Uribe, Mario Masellis et autres

ca, kr (code pays fourni par la source)

Extra‐striatal dopamine in Parkinson's disease with rapid eye movement sleep behavior disorder

Mikaeel Valli, Sang Soo Cho, Mario Masellis, Robert E. Chen et autres

Abstract Rapid eye movement sleep behavior disorder (RBD) is a common condition found in more than 50% of the patients with Parkinson's disease (PD). Molecular imaging shows that PD with RBD (PD‐RBD+) have lower striatal dopamine transporter activity within the caudate and …

ca, es (code pays fourni par la source)

Graph theory analysis of the dopamine D2 receptor network in Parkinson’s disease patients with cognitive decline

Alexander S. Mihaescu, Jinhee Kim, Mario Masellis, Ariel Graff‐Guerrero et autres

Abstract Cognitive decline in Parkinson's disease (PD) is a common sequela of the disorder that has a large impact on patient well‐being. Its physiological etiology, however, remains elusive. Our study used graph theory analysis to investigate the large‐scale topological patterns of the …

ca, es (code pays fourni par la source)