Kieran Gill

Incretin-Based Dual and Triple Agonists in Overweight or Obese Individuals: A Systematic Review and Meta-Analysis

Zhi Hong Chan, Abdousamad Said Omar, Kieran Gill, Gabriele Volucke et autres

Incretin-based dual and triple agonists have emerged as effective options for obesity management, offering enhanced weight loss through multi-receptor agonism. However, data on their efficacy and safety remain limited. We conducted a systematic review and meta-analysis to evaluate the efficacy and safety …

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7-029 Trends and disparities in inflammatory bowel disease and cardiovascular disease-related mortality in the United States from 1999–2023: a CDC wonder analysis

Syed Anjum Gardezi, Insiya Mohammed Rampurawala, Akalanka Ranasinghe, Ali Hasan et autres

Introduction Inflammatory Bowel Disease (IBD) has been associated with an increased risk of cardiovascular disease (CVD) due to chronic systemic inflammation and vascular dysfunction. While advancements in treatment have improved IBD management, its impact on cardiovascular mortality remains unclear. This study aims …

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Trends and disparities in inflammatory bowel disease and cardiovascular disease-related mortality in the United States from 1999 to 2023: A CDC WONDER analysis

Syed Anjum Gardezi, Insiya Mohammed Rampurawala, Akalanka Ranasinghe, Kieran Gill et autres

Background: Individuals with inflammatory Bowel Disease (IBD) may face an increased risk of cardiovascular disease (CVD) due to chronic systemic inflammation and vascular dysfunction. While advancements in treatment have improved IBD management, its impact on cardiovascular mortality remains unclear. This study aims …

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Latest evidence on assessment and invasive management of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) in the older population

Kieran Gill, Gregory B. Mills, Wanqi Wang, Graziella Pompei et autres

INTRODUCTION: Invasive management of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) should be considered regardless of age, but a key challenge is deciding which patients are most likely to benefit from an invasive approach in the older population. In addition to assessment of …

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Updated evidence on selection and implementation of an invasive treatment strategy for older patients with non-ST-segment elevation myocardial infarction

Kieran Gill, Vijay Kunadian

Non-ST-segment elevation myocardial infarction (NSTEMI) is the most common acute coronary syndrome diagnosis in older patients. In the UK, there are ~20 000 NSTEMI cases annually in patients aged ≥75 years. Despite therapeutic advances in pharmacological and invasive management, studies show that …

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Role of Lipoprotein(a) Reduction in Cardiovascular Disease

Uma Heidi Schuth, Kieran Gill, Pyotr Telyuk, Bilal Bawamia et autres

Recent studies have shown that lipoprotein(a) (Lp(a)) is an important risk factor for a plethora of different cardiovascular diseases. It has been proven that Lp(a) levels are genetically determined and correlate with risk of cardiovascular disease, independent of lifestyle factors. As of …

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Role of Lipoprotein(a) Reduction in Cardiovascular Disease

Uma Heidi Schuth, Kieran Gill, Bilal Bawamia, Pyotr Telyuk et autres

Recent studies have shown that Lipoprotein(a) (Lp(a)) is an important risk factor for a plethora of different cardiovascular diseases. It has been proven that Lp(a) levels are genetically determined, and correlate with risk of cardiovascular disease, independent of lifestyle factors. As of …

Role of physiology in the management of multivessel disease among patients with acute coronary syndrome

Nandine Ganzorig, Graziella Pompei, Kenny Jenkins, Wanqi Wang et autres

Multivessel coronary artery disease (CAD), defined as ≥50% stenosis in 2 or more epicardial arteries, is associated with a high burden of morbidity and mortality in acute coronary syndrome (ACS) patients.A salient challenge for managing this cohort is selecting the optimal revascularisation …

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Showdown with Sjogren’s - An Acute Presentation with Right Heart Failure and Cardiogenic Shock

MATTHEW R BEUTNER, Kieran Gill, Vijay P. Balasubramanian