Beatriz Grandal

Causal analyses of the impact of comorbid conditions and concomitant medications on response to neoadjuvant chemotherapy in breast cancer: analysis of a multicenter prospective cohort study (CANTO)

Anne‐Sophie Hamy, Beatriz Grandal, Floriane Jochum, Élise Dumas et autres

BACKGROUND: The incidence of breast cancer (BC) increases with age, together with the frequency of comorbid conditions and chronic concomitant medications. However, little evidence is available regarding their impact on response to treatment in the neoadjuvant setting. MATERIALS AND METHODS: The aim …

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Magnetic surgical marker navigation for excision of non-palpable ultrasound visible breast lesions: first 200 cases in a French cancer center

Vivien Ceccato, Lauren Wallaert, Sophie Michel, Thomas Gaillard et autres

Wire guided localization is widely used as the standard method of pre-operative localization of breast lesions. The aim was to assess outcomes following the introduction of a novel non-wire guided, magnetic surgical marker navigation system. A prospective study between May 2022 and …

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319TiP NeoBREASTIM: A phase II study of atezolizumab plus RP1 oncolytic immunotherapy in the neoadjuvant setting of triple-negative breast cancer (TNBC)

Estelle Bastien, Beatriz Grandal, R. Sanchez, T. Ramtohul et autres

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Sex-related differences in oncological surgery and postoperative outcomes: comprehensive, nationwide study in France

Floriane Jochum, Anne‐Sophie Hamy, Paul Gougis, Élise Dumas et autres

BACKGROUND: The main objective of this study was to undertake an exhaustive investigation of sex-related differences in cancer surgery. METHODS: This observational study used data from the French national health insurance system database covering 98.8% of the population. Patients diagnosed with non-sex-specific …

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Successful excision of non–palpable breast lesions using a magnetic surgical marker navigation system in a specialized French oncologic center

Vivien Ceccato, Lauren Wallaert, Sophie Michel, Thomas Gaillard et autres

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Immune Checkpoint Inhibitor Use During Pregnancy and Outcomes in Pregnant Individuals and Newborns

Paul Gougis, Anne‐Sophie Hamy, Floriane Jochum, Kévin Bihan et autres

Importance: With the widespread use of immune checkpoint inhibitors (ICIs), concerns about their pregnancy outcomes through maternal exposure have emerged, and clinical comparative data are lacking. Objective: To assess the risk of pregnancy-, fetal-, and/or newborn-related adverse outcomes associated with exposure to …

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Initial experience of guided magnetic marker in non-palpable breast excision: first 80 cases in a French centre

Vivien Ceccato, Lauren Wallaert, Thomas Gaillard, Noémie Girard et autres

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Rethinking surgical revisions: impact of the MonarchE trial on axillary dissection in hormone-positive HER2-negative early breast cancer patients potentially eligible for abemaciclib

Thomas Gaillard, Jeanne Piketty, Jean-Guillaume Féron, Noémie Girard et autres

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Effects of gender and socio-environmental factors on health-care access in oncology: a comprehensive, nationwide study in France

Floriane Jochum, Anne‐Sophie Hamy, Paul Gougis, Élise Dumas et autres

Background: Gender-based disparities in health-care are common and can affect access to care. We aimed to investigate the impact of gender and socio-environmental indicators on health-care access in oncology in France. Methods: Using the national health insurance system database in France, we …

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Treatments During Pregnancy Targeting ERBB2 and Outcomes of Pregnant Individuals and Newborns

Paul Gougis, Beatriz Grandal, Floriane Jochum, Kévin Bihan et autres

Importance: Targeted therapies directed against ERBB2 are the cornerstone of medical treatment for ERBB2-positive breast cancers but are contraindicated during pregnancy. Objectives: To describe the association of exposure to anti-ERBB2 agents during pregnancy with pregnancy and fetal or newborn outcomes, and to …

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Abstract P3-07-06: Comedications at Breast Cancer diagnosis impact overall survival: results from the ADRENALINE (Atlas for DRug and brEast caNcer survivAL INtEraction) study (n=235,368)

Élise Dumas, Beatriz Grandal, Paul Gougis, Sophie Houzard et autres

Abstract Background: More than half of Breast Cancer (BC) patients take chronically used non-cancer treatments (denoted as comedications) at BC diagnosis. Epidemiological evidence has reported that several non-cancer treatments may modify BC risk, BC recurrence, and overall survival (OS). The ADRENALINE project …

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Evolution of synchronous female bilateral breast cancers and response to treatment

Anne‐Sophie Hamy, J. Abécassis, Keltouma Driouch, Lauren Darrigues et autres

Synchronous bilateral breast cancer (sBBC) occurs after both breasts have been affected by the same germline genetics and environmental exposures. Little evidence exists regarding immune infiltration and response to treatment in sBBCs. Here we show that the impact of the subtype of …

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