Profil bibliographique

Yuka Nakamura

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

3Publications signalées
0Citations signalées
1Affiliations récentes

Les institutions déclarées

Kumamoto University

Les domaines associés

Glycosylation and Glycoproteins ResearchMonoclonal and Polyclonal Antibodies ResearchDrug Transport and Resistance MechanismsAI in cancer detectionBiochemical and Molecular Research

Les publications récentes

2024 article OpenAlex

Contribution of Phe112, Ser114, and Tyr115 to Drug-Binding Selectivity in the A Variant of α1-Acid Glycoprotein

Yuka Nakamura, Hiroshi Watanabe, Teruya Nakamura, Mami Chirifu et autres

-acid glycoprotein (AGP) primarily affects the pharmacokinetics of basic drugs. There are two AGP variants in humans, A and F1*S, exhibiting distinct drug-binding selectivity. Elucidation of the drug-binding selectivity of human AGP variants is essential for drug development and personalized drug therapy. …

jp (code pays fourni par la source)

0 citations Molecular Pharmaceutics
2024 article OpenAlex

Contribution of the α1-Acid Glycoprotein in Drug Pharmacokinetics: The Usefulness of α1-Acid Glycoprotein-Knockout Mice

Yuka Nakamura, Hiroshi Watanabe, Tadashi Imafuku, Issei Fujita et autres

α 1 -Acid glycoprotein (AGP) is a primary binding protein for many basic drugs in plasma. The number of drugs that bind to AGP, such as molecular target anticancer drugs, has been continuously increasing. Since the plasma level of AGP fluctuates under …

jp (code pays fourni par la source)

0 citations Molecular Pharmaceutics
Notice OpenAlex

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