Afaf Elsaid

Genetic variation in IL-6 rs1800796 and its association with non-Hodgkin lymphoma susceptibility in the Egyptian population

Heba Shamshoun, Mai M. Madkour, Afaf Elsaid, Sherif Refaat et autres

Égypte (code pays fourni par la source)

Combining prognostic value of FGFR3 polymorphism and interleukin-1β status for enhanced prognostic stratification in bladder cancer

Afaf Elsaid, Riyad T Mukhlif, Manar Abdelkhalek, Hassan Abol-Enein et autres

Égypte (code pays fourni par la source)

Cycloxygenase-2 (−765G>C) gene polymorphism and risk of uterine fibroids in Egyptian women

Y. El-Sayed, Afaf Elsaid, mohamed eid, Ahmed Khairul Hasan

Égypte (code pays fourni par la source)

Association between Nitric Oxide Production in Preeclampsia and Variations in the Endothelial Nitric Oxide Synthase Gene

Enas A Oraby, Mohamed Ahmed Abd Elmoneim, Shereen Ahmed Elwasefy, Nanis S. El-Beltagy et autres

Background: Preeclampsia (PE) is a multifactorial hypertensive pregnancy illness.Many factors are involved in regulating endothelial function; however, the development of PE appears to be primarily influenced by the endothelial nitric oxide synthase (eNOS) gene.This study examined the association of the eNOS 4b/4a, …

Égypte, sa, us (code pays fourni par la source)

Association of vitamin D receptor gene polymorphisms ApaI (rs7975232) and BsmI (rs1544410) with hepatocellular carcinoma susceptibility in Egyptian patients

Salma Saleh Alrdahe, Aishah E. Albalawi, Doaa Bahaa Eldin Darwish, Awatif M. E. Omran et autres

sa, Égypte (code pays fourni par la source)

Genetic insights into acute lymphoblastic leukemia: the role of MDR1 and IL18 polymorphisms in Egyptian children

Ali Mahdi, Afaf Elsaid, Mai M. Madkour, A. F. Abdel-Aziz

BACKGROUND: The most prevalent cancer in pediatric is acute lymphoblastic leukemia (ALL). The multidrug resistance gene (MDR1) encodes the membrane transport protein P-glycoprotein (P-gp), which acts as an efflux pump. Interleukin 18 (IL18), an 18-kilodalton cytokine, plays a complex role in cancer, …

Égypte (code pays fourni par la source)

Role of vitamin D receptor FokI (rs10735810)variant in breast cancer susceptibility

Hadir Khedr, Abdel-Aziz Fatouh Abd-Aziz, Afaf Elsaid, Sherif Refaat

Breast cancer (BC) has a significant morbidity and death rate and accounts for a disproportionate percentage of healthcare costs. It affects one of every eight women during her lifetime.BC has various genetic mutation disorders, including the VDR FokI polymorphism. The aim of …

Égypte (code pays fourni par la source)

Investigation of the Effects of B7H4 (rs10754339 A>G) Gene Polymorphism and Serum Level on Breast Cancer Susceptibility

Kamal Jwameer Owaid, Afaf Elsaid, Manar Refaat Abdel Khalek, Abdel-Aziz Fetouh

BACKGROUND: The prevalence of breast cancer groups requires further clarification to understand the mechanisms leading to its development. B7H4 is a novel immune checkpoint protein that negatively regulates T cell activation and function. It is overexpressed in several cancers and breast cancer …

Égypte (code pays fourni par la source)

CYP3A4 and CYP3A5 Genes in Cyclophosphamide-treated Chronic Lymphocytic Leukemia Patients: A Pharmacogenetics Study

Heba Mostafa El-Maraghy, Menna Al-Adl, Eman R. Saifeldein, Sahar Elashmony et autres

Background: Approximately 75% of drug metabolism in clinical settings is attributed to cytochrome P450 enzymes. This study aimed to assess the effects of the CYP3A4*1B and CYP3A5*3 genetic variations on the clinical results of individuals with chronic lymphocytic leukemia (CLL) following cyclophosphamide …

Égypte, sa (code pays fourni par la source)

Association between PAI-1 gene − 657 4G/5G polymorphism and preeclampsia in Egyptian women: a case-control study

Omali Y. El‐khawaga, Afaf Elsaid, Hwyda Ahmed, Aliaa N El-Daw et autres

Pre-eclampsia constitutes a pregnancy disease characterized by hypertension and proteinuria, as well as dysregulation of the coagulation cascade and hypo fibrinolysis that affects many systems. The purpose of this study is to examine the connection between (-657 4G/5G PAI-1) and the danger …

Égypte, iq (code pays fourni par la source)

Interleukins 10 and 1β gene polymorphisms in ischemic stroke risk in the Egyptian population

Omali Y. El‐khawaga, Afaf Elsaid, Wessam Mustafa, Aliaa N El-Daw et autres

Stroke remains the leading cause for lasting disability and death globally. Two frequent proinflammatory cytokine variants in the IL-10 and IL-1β genes, rs16944 T/C and rs1800896 G/A, may be major candidate gene loci impacting ischemic stroke vulnerability. The present case-control research aims …

Égypte (code pays fourni par la source)

The influence of single-nucleotide polymorphisms in opioid receptors genes on opioid use disorder susceptibility among Egyptian population: A case-control study

Amira A. Abdelnoor, Mostafa Mamdouh Kamel, Fatma Elgazzar, Afaf Elsaid et autres

Égypte (code pays fourni par la source)