Discovery of a Novel Lidocaine Metabolite by Human Liver Microsome and Identification of Microbial Species Which Produces the Same Metabolite
Sho Hori, Hikari Taniguchi, Sota Yoshimura, Kanako Takeda et autres
Preparation of drug metabolites at the milligram scale is essential for determining the structure and toxicity of drug metabolites. However, their preparation using recombinant proteins and human liver microsomes (HLM) is often difficult because of technical and ethical issues. Reproducing human drug …
jp (code pays fourni par la source)
1 citation
Chemical and Pharmaceutical Bulletin