Yuhang Quan

Effects of sevoflurane inhalation anesthesia versus propofol intravenous anesthesia on postoperative cognitive function in patients with malignant tumors: A meta-analysis

Yuhang Quan, Mingxiong Zhang, Mengqiu Zheng, Min Zhao et autres

BACKGROUND: Both propofol and sevoflurane, commonly used anesthetics, may cause brain oxygen metabolism abnormalities potentially linked to postoperative cognitive dysfunction (POCD), though their precise relationship with POCD requires further study. OBJECTIVE: To systematically evaluate sevoflurane inhalation versus propofol intravenous anesthesia effects on …

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Network meta-analysis of different liver protective drugs in the treatment of drug-induced liver injury

Chengcheng Li, Xin Yang, Yuhang Quan, Anhao Wu et autres

BACKGROUND: Currently, drug-induced liver injury (DILI) has become one of those public issues in society, which has added a huge burden to both the individuals and the society. In the current clinical stage, there are numerous drugs developed to treat this disease, …

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YTHDF1 enhances stemness and chemoresistance in triple‐negative breast cancer cells by upregulating SIAH2

Anhao Wu, Xi Wang, Fang Zhang, Xin Yang et autres

Triple-negative breast cancer (TNBC) is the most lethal and aggressive subtype of breast cancer, and chemoresistance is the major determinant of TNBC treatment failure. This study explores the molecular mechanism of TNBC chemoresistance. The Cancer Genome Atlas, breast cancer integrative platform, and …

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Network meta-analysis of different liver protective drugs in the treatment of drug-induced liver injury

Chengcheng Li, Xin Yang, Yuhang Quan, Yafang Lai et autres

Participant or populationBecause this is a systematic review of the protocol and a network meta-analysis, all the data in this study are from published studies and do not involve patients. Intervention Not applicable.Comparator Not applicable. Study designs to be includedThis study collected …

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Effects of sevoflurane inhalation anesthesia versus propofoen intravenous anesthesia on postoperative cognitive function in patients with malignant tumors：Meta-analysis

mingxiong zhang, Yuhang Quan

sevoflurane inhalation anesthesia versus propofoen intravenous anesthesia on postoperative cognitive function in patients with malignant tumors：Metaanalysis.Inplasy protocol 202350107.

Pivotal models and biomarkers related to the prognosis of breast cancer based on the immune cell interaction network

Rui Liu, Xin Yang, Yuhang Quan, Yiyin Tang et autres

The effect of breast cancer heterogeneity on prognosis of patients is still unclear, especially the role of immune cells in prognosis of breast cancer. In this study, single cell transcriptome sequencing data of breast cancer were used to analyze the relationship between …

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Propofol and Sevoflurane Alleviate Malignant Biological Behavior and Cisplatin Resistance of Xuanwei Lung Adenocarcinoma by Modulating the Wnt/β-catenin Pathway and PI3K/AKT Pathway

Zhonghui Wang, Yuhang Quan, Shanshan Li, Yahong Wang et autres

BACKGROUND: Recent studies have shown that propofol and sevoflurane, two common anesthetics, can prevent tumor development. The prevalence of lung adenocarcinoma in China is highest in Yunnan Xuanwei, and many patients with lung cancer in this area are often resistant to platinum-based …

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[Retracted] Bioinformatics Analysis of the Characteristics and Correlation of m6A Methylation in Breast Cancer Progression

Ping Zhao, Xinwei Huang, Anhao Wu, Xin Yang et autres

Growing cutting-edge study has demonstrated the RNA m6A methylation's critical role in regulating tumorigenesis and progression all over the world, while it is still a mystery whether RNA m6A methylation has a positive impact on breast cancer treatment. In this article, we …

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Bioinformatics Analysis of Pivotal Module and Biomarkers Related to the Prognosis of Breast Cancer Based on Single-cell Transcriptome Data

Rui Liu, Xin Lin Yang, Yuhang Quan, Yiyin Tang et autres

Abstract Background: The effect of breast cancer heterogeneity on prognosis of patients is still unclear, especially the role of immune cells in prognosis of breast cancer. Therefore, the discovery of new markers to assess the effect of breast cancer heterogeneity on patient …

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Bioinformatics Analysis the Characteristics and Correlation of m6A Methylation in Breast Cancer Progression

Ping Zhao, Xinwei Huang, Anhao Wu, Xin Yang et autres

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Bioinformatics Analysis the Expression Characteristics of RNA m6A Methylation Regulator in Breast Cancer Progression

Ping Zhao, Xinwei Huang, Anhao Wu, Xin Yang et autres

Abstract Background: RNA m6A methylation regulator has been shown to play an important regulatory role in tumorigenesis and progression. However, the role and characteristics of RNA m6A methylation in breast cancer are not yet clear. Objective: To analyze the effect of the …

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Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells

Shanshan Li, Hui Yang, Min Zhao, Linli Gong et autres

Propofol (2,6‑diisopropylphenol) is one of the most commonly used intravenous anesthetics and possesses a number of non‑anesthetic effects, including antitumor function. The aim of the present study was to elucidate the antitumor molecular mechanism of propofol on A549 and H1299 cells. A549 …

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