M A Orlova

Conventional and Tropism-Modified High-Capacity Adenoviral Vectors Exhibit Similar Transduction Profiles in Human iPSC-Derived Retinal Organoids

Andrew J. McDonald, Carmen Gallego, Charlotte A. Andriessen, M A Orlova et autres

Viral vector delivery of gene therapy represents a promising approach for the treatment of numerous retinal diseases. Adeno-associated viral vectors (AAV) constitute the primary gene delivery platform; however, their limited cargo capacity restricts the delivery of several clinically relevant retinal genes. In …

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Conventional and Tropism-Modified High-Capacity Adenoviral Vectors Exhibit Similar Transduction Profiles in Human iPSC-Derived Retinal Organoids

Andrew J. McDonald, Carmen Gallego, Charlotte A. Andriessen, M A Orlova et autres

Viral vector delivery of gene therapy represents a promising approach for the treatment of numerous retinal diseases. Adeno-associated viral vectors (AAV) constitute the primary gene delivery platform; however, their limited cargo capacity restricts the delivery of several clinically relevant retinal genes. In …

Characterization and AAV-mediated CRB gene augmentation in human-derived CRB1KO and CRB1KOCRB2+/− retinal organoids

Nanda Boon, Xuefei Lu, Charlotte A. Andriessen, M A Orlova et autres

The majority of patients with mutations in CRB1 develop either early-onset retinitis pigmentosa as young children or Leber congenital amaurosis as newborns.The cause for the phenotypic variability in CRB1-associated retinopathies is unknown, but might be linked to differences in CRB1 and CRB2 …

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Geographic analysis of environmental assessment results of agricultural land in Samara region

Elena V. Samokhvalova, Sergey Zudilin, O A Lavrennikova, J S Iralieva et autres

The study presents spatial analysis of agricultural land degradation in the Samara Region with an assessment of economic losses under the influence of negative factors. The characteristics of ecological state of lands are made in the context of administrative districts on the …

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TOPCONS - Transboundary tools for spatial planning and conservation of the Gulf of Finland

E. O. Chernova, Y Russkikh, M A Orlova, F Uspenskiy et autres

Взаимосвязь агрегирования наночастиц, несущих ионы цинка, с цитотоксичностью и морфологией клеток крови

M A Orlova, Е. Ю. Осипова, С. А. Румянцев, Д.А. Зайцев

Four-wave parametric oscillation in a transversely pumped system

Boris Ya Zel'dovich, M A Orlova, Vladimir V. Shkunov

The variational principle is used to derive a system of equations describing the four-wave parametric oscillation in a medium with a reactive cubic nonlinearity. In the case of a transversely pumped configuration the integrals of the system can be used to obtain …

Four-wave parametric lasing in a scheme with transverse pumping

B. Ia. Zel'Dovich, M A Orlova, Vladimir V. Shkunov

Accuracy of wavefront reversal in stimulated scattering with a frequency and angular shift

Boris Ya Zel'dovich, M A Orlova

An analysis is made of distortions of the reversed wave in stimulated backscattering of light (backward WFR) caused by frequency and angular shifts of the scattered wave relative to the pump wave. The scattered field is expressed in the form of a …

The Reactivity of Hydrogen Atoms

Э.С. Филатов, Е.Ф. Симонов, M A Orlova

Theoretical ideas about the reactions of thermal and hot hydrogen atoms are examined and experimental data, characterising the mode of reactions involving hydrogen atoms with different energies, are presented. The bibliography includes 212 references.

Реакционная способность атомов водорода

Э.С. Филатов, Е.Ф. Симонов, M A Orlova

Nonstationary theory and calculation of the time of establishment of four-wave wave-front reversal

Boris Ya Zel'dovich, M A Orlova, Vladimir V. Shkunov