Tiffany Seto

8 Pembrolizumab (P) +/– lenvatinib (L) in patients with advanced endometrial cancer (EC) in northern California

Tiffany Seto, Richie Houhong Xu, Lue-Yen S. Tucker, Michael A. Bookman

More effective treatments are needed for women with advanced or recurrent EC. P+L received FDA approval JUL2021 for recurrent EC with proficient (p) MisMatch Repair (MMR). P received FDA approval MAR2022 for deficient (d) MMR advanced EC. Addition of L is associated …

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Risk Factors Predictive of Cardiac Toxicities from Ibrutinib: A Community-Based Retrospective Cohort Study of Patients with NHL in Northern California

Tiffany Seto, Kelli Peterman, Deepika Kumar, Jonathan G. Zaroff et autres

Background: Ibrutinib is a tyrosine kinase inhibitor (TKI) known to be effective in treating multiple hematologic malignancies. Although generally well tolerated, significant cardiac toxicities including atrial fibrillation, sudden cardiac death, and hypertension may occur shortly after starting therapy with ibrutinib. We aimed …

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Pain as Initial Presenting Symptom Is Associated With Delay to Seeking Medical Attention, Higher Risk of Relapse, and Shorter Survival in Patients With Early-Stage Extremity or Trunk Synovial Sarcoma

Tiffany Seto, Maqdooda A. Merchant, Lee Jae Morse, Andrew S. Fang et autres

BackgroundWhether the presenting symptom of pain vs mass impacts survival of early-stage synovial sarcoma is not known. Patients and MethodsThe authors investigated patients with early-stage extremity/trunk synovial sarcoma diagnosed from 2005 to 2017 at Kaiser Permanente Northern California for associations between the …

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Treatment patterns for patients with metastatic or recurrent head and neck cancer in a large integrated health-care system.

Tiffany Seto, Navendu D. Samant, Nina D. Shah, Aida Shirazi et autres

e18015 Background: Since publication of the landmark KEYNOTE-048 Trial, pembrolizumab alone or with platinum-based chemotherapy and 5-fluorouracil (5FU) was established as a standard of care for the frontline treatment of patients with recurrent or metastatic head and neck squamous cell cancer (HNSCC), …

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Fourteen-Day Gemcitabine-Docetaxel Chemotherapy Is Effective and Safer Compared to 21-Day Regimen in Patients with Advanced Soft Tissue and Bone Sarcoma

Minggui Pan, Maily K. Trieu, Manpreet K. Sidhu, Jeanette Cu Yu et autres

Gemcitabine-docetaxel (G-D) combination is an effective chemotherapy for patients with advanced soft tissue and bone sarcoma, first developed with G administered on days 1 and 8, and D on day 8 every 21 days and later modified to be administered every 14 …

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Impact of a Virtual Multidisciplinary Sarcoma Case Conference on Treatment Plan and Survival in a Large Integrated Healthcare System

Minggui Pan, Jeanette Cu Yu, Manpreet K. Sidhu, Tiffany Seto et autres

PURPOSE: Quantifying the impact of a multidisciplinary cancer case conference on patient outcome and care quality remains challenging. PATIENTS AND METHODS: We prospectively investigated the impact of our virtual multidisciplinary sarcoma case conference (VMSCC) on treatment plan in patients presented to the …

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Feasibility and Value of Establishing a Community-Based Virtual Multidisciplinary Sarcoma Case Conference

Minggui Pan, Tiffany Seto, Jeanette Cu Yu, Manpreet K. Sidhu et autres

PURPOSE: Management of soft tissue and bone sarcoma presents many challenges, both diagnostically and therapeutically, and requires multidisciplinary collaboration; however, such collaboration is often challenging to establish, especially in the community setting. We share our experiences of a virtual multidisciplinary sarcoma case …

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Long-Term Outcomes of Ventral Hernia Repair: An 11-Year Follow-Up

Nikita Kadakia, Ross Mudgway, Jonathan C. Vo, Vinson Vong et autres

BACKGROUND: Ventral hernia repair (VHR) is one of the most common general surgery procedures; however, few studies with long-term follow-up of VHR outcomes exist. METHODS: We performed a retrospective review of VHRs performed from 2000 to 2009 at a single institution. Our …

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Feasibility and Value of Establishing a Community-Based Virtual Multidisciplinary Sarcoma Case Conference

Minggui Pan, Tiffany Seto, Jeanette Cu Yu, Manpreet K. Sidhu et autres

PURPOSE: Management of soft tissue and bone sarcoma presents many challenges, both diagnostically and therapeutically, and requires multidisciplinary collaboration; however, such collaboration is often challenging to establish, especially in the community setting. We share our experiences of a virtual multidisciplinary sarcoma case …

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Prevalence of delay to seeking medical attention in patients with synovial sarcoma and association with inferior outcomes.

Tiffany Seto, Mee-Na Song, Elizabeth Russell, Danny L. Sam et autres

e23556 Background: Synovial sarcoma is an aggressive soft tissue sarcoma that predominantly affects young patients with high rate of relapse and mortality. Systemic study of patients’ presenting symptoms and possible delay of seeking medical attention is lacking. Methods: We retrospectively reviewed the …

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Long-Term Outcomes of Mesh and Primary Ventral Hernia Repair

Nikita Kadakia, Ross Mudgway, Jonathan C. Vo, Tiffany Seto et autres

Kadakia, Nikita; Mudgway, Ross; Vo, Jonathan MD; Seto, Tiffany MD; Ge, Shaokui PhD; Vong, Vinson; Depew, Aron MD, FACS; Bortz, Pascal MD Author Information

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Germline BRCA1 Deletion as Driver Mutation for Metastatic Urachal Adenocarcinoma in Patient Who Achieved Complete Response to Rucaparib

Tiffany Seto, Deepti Pujare, Mee-Na Song, JASON KAI WEI LEE et autres

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