Kang

Effect of heating rate on nano-structured carbonization of γ-cyclodextrin microcube

Kang

Nickel(II)âassisted enantiomeric differentiation and quantitation of tadalafil by direct electrospray ionization mass spectrometry

Wang, Chai Chai, Kang, Sun et autres

Cellular model of neuronal atrophy induced by DYNC111 deficiency reveals protective roles of RAS-RAF-MEK signaling

Zhi-Dong, Liu, Su, Chang Xian Zhang et autres

Toward a Molecular Understanding of Plant Hormone Actions

Chuanyou, Li, Jiayang, Kang et autres

Appropriate choice of collision-induced dissociation energy for qualitative analysis of notoginsenosides based on liquid chromatography hybrid ion trap time-of-flight mass spectrometry

Guang-ji, Fu, Han-Xu, Xiao Xiao et autres

Liquid chromatography hybrid ion trap/time-of-flight mass spectrometry possesses both the MS~n ability of ion trap and the excellent resolution of a time-of-flight and has been widely used to identify drug metabolites and determine trace multi-components in natural products. Collision energy, one of …

A rapid method for chemical fingerprint analysis of Panax notoginseng powders by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

LIUPeng, Yu, He-Shui, Zhang et autres

A method coupling ultra-performance liquid chromatography(UPLC) with quadrupole time-of-flight mass spectrometer(Qtof MS) using the electrospray ionization(ESI) source was developed for the identification of the major saponins from Panax notoginseng powder(PNP). Ten different PNP samples were analyzed and evaluated for their quality by …

Changing provenance of late Cenozoic sediments in the Jianghan Basin

Lei Lei, Shao Shao, Shengyuan, Yuan et autres

The Yangtze River is one of the most important components of the East Asia river system.In this study,sediments in the Jianghan Basin,middle Yangtze River,were selected for trace element and rare earth element(REE)measurements,in order to decipher information on the change of sediment provenance …

Chemical composition, mechanism of antibacterial action and antioxidant activity of leaf essential oil of Forsythia koreana deciduous shrub

Xiaonan, Yang Yang, Imran Imran, Khan et autres

Objective: To identify the chemical constituents of leaf essential oil of Forsythia koreana(F. koreana) and evaluate its ef ects on bacterial strains. Methods: The essential oil of leaf of F. koreana was extracted by using hydrodistillation process and the volatile components investigated …

Determination of reference intervals for metabolic profile of Hanwoo cows at early, middle and late gestation periods

Chuan chuan, Piao, Tao Tao, Wang et autres

Background: Metabolic profile was initially designed as a presymptomatic diagnostic aid based on statistical analyses of blood metabolites to provide an early warning of certain types of metabolic disorder. However, there is little metabolic profile data available about Korean Hanwoo cows. Therefore, …

A three-dimensional modeling of the morphological change in the Liaodong Bay

Qiu-shun, Haigui, Kang

在 Liaodong 海湾的形态学由于附近的河的截止在过去的十年经历了一个显著变化。海湾的好沉积在海床上与相对小的粒子由非连贯、连贯的部分组成。因此，没有沉积输入，为非连贯、连贯的部分的三维的 morphodynamic 模型财务从附近的河被建立调查词法变化。一个代表性的波浪被选择在 Liaodong 海湾计算波浪分发，深度依赖者波浪放射压力被水动力学模型采用。移流散开方程被用来在代表性的波浪和潮汐的水流下面模仿好沉积运输。非连贯、连贯的沉积的侵蚀流动被考虑。潮汐的水平，速度，方向，和沉积集中的模仿的结果与测量数据一致。结果证明现在的模型，考虑 noncohesive 和连贯的部分的侵蚀流动，给更合理的价值比什么时候为连贯的沉积的财务独自一个。当三维的 morphodynamic 模型被使用在一年的功课上预言词法变化时，免职被显示相对小，侵蚀的范围从河与沉积输入的以前的结果相比被增加。在 Liaodong 海湾的侵蚀由于河的截止正在增加，这能被结束，并且如果沿海的构造计划的任何类型将在海床上被执行，那词法进化必须被考虑。

Base pair distance analysis in single DNA molecule by direct stochastic optical reconstruction microscopy

Suresh, Kumar, Chakkarapani, Guenyoung et autres

为基础对距离分析的单个 -DNA 分子的精确荧光成像要求一种超级决定的技术，因为这些距离大概衍射限制。单个 -DNA 分子设置了与荧光灯染料 YOYO-1 在 subdiffraction 被调查由直接随机的光重建显微镜学(dSTORM ) 的空间分辨率。各种各样的 dye-to-DNA 底对比率被 photoswitching YOYO-1 在之间想象荧光灯用二激光的状态和黑暗状态采购原料。获得的图象被使用适合到点传播函数的矩心的 Gaussian 重建进一幅超级决定的图象。由测量在局部性的 fluorophores 之间的距离，在为 1:50 ， 1:100 ，和 1:500 的 dye-to-DNA 底对比率的单个 DNA 分子的基础对距离被计算是 17.1 &#xA0 ； ±&#xA0 ； 0.8 &#xA0 ； nm ， 34.3 &#xA0 …

UPLC-MS／MS法测定口服银杏叶片的大鼠血浆中七种活性成分及药代动力学研究

Wenping, Wang, Liu, Qian Qian et autres

研究目的：建立一个快速灵敏且具有专属性的体内分析方法用于银杏叶片的药代动力学研究。 创新要点：运用超高压液相色谱-二级质谱连用法（UPLC-MS／MS）进行大鼠血浆中七种活性成分的测定，方法简单快速，适合于银杏叶制剂的药代动力研究。 研究方法：采用液液萃取进行血浆样品处理，该方法简单且快速。采用超高压液相色谱（UPLC）进行七种活性成分分离，达到了多种成分快速分离的目的。采用二级质谱（MS／MS）进行检测，优化质谱条件，减小了内源性干扰并提高检测灵敏度。经过专属性、线性、回收率、基质效应、精密度、准确度和稳定性考察，验证了该方法的适用性。经验证，该方法适用于银杏叶片的药代动力学研究。 重要结论：液液萃取处理血浆样品简单可靠，回收率稳定，无基质效应（表4）。UPLC-MS／MS能够快速、灵敏、专属性地分析大鼠血浆七种活性成分的血药浓度（表3和图3）。该方法适用于银杏叶片的七种活性成分的药代动力学研究（图4和5）。