Seung-Hwan Woo

Alpha‐Ketoisocaproate Attenuates Muscle Atrophy in Cancer Cachexia Models

Pooreum Lim, Seung-Hwan Woo, Jihye Han, Young Lim Lee et autres

BACKGROUND: Cancer-associated cachexia (CAC) is a multifactorial syndrome characterised by progressive loss of muscle mass with limited Food and Drug Administration treatments. Although emerging evidence suggests that l-leucine and β-hydroxy-β-methyl butyrate (HMB) have potential for treating CAC, the role of α-ketoisocaproate (KIC), …

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Extract of Litsea japonica (Thunba.) Jussieu Fruit Reduces Muscle Atrophy in Cancer Cachexia

Seung-Hwan Woo, Pooreum Lim, Jihye Han, Ho Jin Kang et autres

ABSTRACT Cancer cachexia is a complex syndrome involved in muscle wasting, fat depletion, fatigue, reduced appetite, and unintentional weight loss. Recent studies have suggested that natural products can prevent cancer cachexia; however, there have been no studies on the effects of Litsea …

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Effects of alpha-ketoisocaproate in oxidative stress-induced C2C12 myotubes via inhibition of p38 MAPK and ERK1/2

Pooreum Lim, Seung-Hwan Woo, Jihye Han, Young Lim Lee et autres

Sarcopenia is an age-related muscle atrophy characterized by decreased muscle mass and function. However, potential treatments to alleviate sarcopenia remain limited. In this study, we investigated the effects of α-ketoisocaproate (KIC) on C2C12 differentiation and reactive oxygen species (ROS)-induced atrophy in C2C12 …

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Danshensu sodium salt alleviates muscle atrophy via CaMKII ‐ PGC1α ‐ FoxO3a signaling pathway in D‐galactose‐induced models

Pooreum Lim, Seung-Hwan Woo, Jihye Han, Young Lim Lee et autres

Sarcopenia is an age-related muscle atrophy syndrome characterized by the loss of muscle strength and mass. Although many agents have been used to treat sarcopenia, there are no successful treatments to date. In this study, we identified Danshensu sodium salt (DSS) as …

kr (code pays fourni par la source)

Strengths‐Based Assessment and Inclusive Language for Patients With Intellectual and Developmental Disabilities

S. K. Jain, Karishma Shah, Seung-Hwan Woo, Morgan Dykman et autres

Pediatric dermatology patients with intellectual and developmental disabilities (IDD) and comorbid cutaneous conditions often face barriers to effective healthcare due to differences in communication preferences and sensitivities to environmental factors. The clinical intake process serves as a potential intervention point to help …

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Phenomenological Study on Experience of Stomach Cancer Survivors

Myungsun Yi, Hye‐Young Jang, Seung-Hwan Woo, Hye Sook Kim

IL-15 expression in skeletal muscle by resistance exercise training in type 2 diabetic rats

Wook Jae Song, D. Kim, Hye Jin Kim, Seung-Lyul Oh et autres

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The effect of self-directed exercise program on physical function of older adults with frailty

Wook Jae Song, Seung-Hwan Woo, Sarah Soyeon Oh, Hee Jung Kim et autres

kr (code pays fourni par la source)

Outcome Variation in Non-Small Cell Lung Cancer Patients with Solitary Brain Metastasis

Chenhao Hu, Eric M. Chang, Samuel J. Hassenbusch, Pamela Allen et autres