Morena Giovannelli

Effects of Continuous Infusion Therapies on Non-Motor Symptoms in Advanced Parkinson’s Disease: A Systematic Review

Domiziana Rinaldi, Lanfranco De Carolis, Claudia Ledda, S. Galli et autres

Background/Objectives: Non-motor symptoms (NMS) are highly prevalent in advanced Parkinson’s disease (PD) and substantially affect quality of life. Continuous infusion therapies are established treatment options for motor fluctuations not controlled by oral medication, but their effects on NMS remain incompletely characterized. We …

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Unraveling gait and balance impairment in cervical dystonia: associated features, functional implications, and the effect of botulinum toxin

S. Galli, Claudia Ledda, Silvia Gallo, Maurizio Zibetti et autres

BACKGROUND: Cervical dystonia (CD) may affect not only head posture but also gait and balance. The relationship between quantitative gait abnormalities and perceived disability, the contribution of head tremor (HT) and the impact of botulinum toxin (BoNT) on these disturbances remain unclear. …

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Spasticity Management with Botulinum Toxin in Post-stroke and Multiple Sclerosis Patients: A Retrospective, ‘Real-world’, Multicenter Study

Calogera Butera, Marcello Esposito, Assunta Trinchillo, Morena Giovannelli et autres

Background While there is strong evidence for botulinum toxin-A (BoNT-A) in post-stroke spasticity, there is a paucity of data in multiple sclerosis and other conditions in real-world settings. Objective Document the use of BoNT-A in the management of spasticity, with focus on …

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Spasticity patterns assessment and recognition for therapeutic approaches (SPARTA) in multiple sclerosis: a multicenter epidemiological study

Paolo De Blasiis, Andrea Massimiani, Cristina Inglese, Edoardo Bianchini et autres

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Comprehensive Observational and Longitudinal study on the Outbreak of Stroke-related Spasticity focusing on the Early Onset management with Botulinum NeuroToxin (COLOSSEO-BoNT): protocol for a real-world prospective observational study on upper limb spasticity

Massimo Marano, Antonio Suppa, Maria Giuseppina Palmieri, Emanuela Cecconi et autres

INTRODUCTION: Poststroke spasticity (PSS) affects up to 40% of patients who had a stroke. Botulinum neurotoxin type A (BoNT-A) has been shown to improve spasticity, but the optimal timing of its application remains unclear. While several predictors of upper limb PSS are …

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A case of idiopathic lower limb dystonia treated with combined botulinum toxin and phenol nerve block

Edoardo Bianchini, Andrea Massimiani, Jonathan Bemporad, Morena Giovannelli

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The tolerability, safety and efficacy of safinamide in elderly Parkinson’s disease patients: a retrospective study

Domiziana Rinaldi, Edoardo Bianchini, Michela Sforza, Marika Alborghetti et autres

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Botulinum toxin for the management of spasticity in multiple sclerosis: the Italian botulinum toxin network study

Marcello Moccia, Jessica Frau, Antonio Carotenuto, Calogera Butera et autres

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Determinants of botulinum toxin discontinuation in multiple sclerosis: a retrospective study

Pamela Latino, Letizia Castelli, Luca Prosperini, Maria Rita Marchetti et autres

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Levodopa/Carbidopa Intestinal Gel for Treatment of Advanced Parkinson’s Disease: An Update on the Effects of Cognitive Functions

Pamela Latino, Stefania Tagliente, Clelia Pellicano, Morena Giovannelli et autres

Cognitive impairment is a frequent non-motorsymptom of Parkinson’s disease (PD). In early disease stage, this takes the features of dysexecutive syndrome, and is mostly dependent on derangement of frontostriatal circuitries. In advanced stages, worsening of dysexecutive symptoms is accompanied by disorientation and …

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Botulinum toxin type A for Holmes tremor secondary to thalamic hemorrhage

Pamela Latino, Francesco E. Pontieri, Francesco Orzi, Morena Giovannelli

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Treatment with botulinum toxin for anti-MAG neuropathy-related arm tremor

Pamela Latino, Clelia Pellicano, Francesco E. Pontieri, Morena Giovannelli

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