Mohammad Jarrar

Real-World Experience with CPX-351 for Secondary Acute Myeloid Leukemia: Comparison with FLAG-IDA in a Propensity Score Matching Analysis

María Agustina Perusini, Claire Andrews, Eshetu G. Atenafu, Sarit Assouline et autres

CPX-351 is approved for therapy-related acute myeloid leukemia (t-AML), and AML with myelodysplastic-related changes (AML-MRC). This approval was based on improved survival, remission rates, and similar safety compared to 7+3 regimen. In clinical practice, FLAG-IDA, followed by Allogenic Stem Cell transplant (ASCT) …

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Presentation and Outcome of Patients with Multiple Myeloma (MM), Single Centre Experience from Windsor Essex Regional Cancer Centre

Dalia Kashash, Eric McArthur, Caroline Hamm, Rasna Gupta et autres

Introduction: Outcomes for patients with multiple myeloma has significantly improved through the years. This is mainly related to the use of novel agents. Methods: This is a retrospective study that reviewed presentation and outcome of 139 patients with multiple myeloma at the …

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Human leucocyte antigen‐matched related haematopoietic stem cell transplantation using low‐dose cyclophosphamide, fludarabine and thymoglobulin in children with severe aplastic anaemia

Abdulrahman Alsultan, Rodaina Abujoub, Reem Al‐Sudairy, Shahbaz Memon et autres

When human leucocyte antigen-matched related donors are available, haematopoietic stem cell transplantation (HSCT) in children with severe aplastic anaemia (SAA) represents the standard of care. Cyclophosphamide (Cy) 200 mg/kg and anti-thymocyte globulin (ATG) are frequently administered, but to-date, no standard conditioning regimen …

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The tale of two organs: allogeneic hematopoietic stem cell transplantation following liver transplantation in a myelofibrosis patient

Donald Bastin, Gillian Mount, Cyrus C. Hsia, Mohammad Jarrar et autres

T a g g e d H 1 IntroductionT a g g e d E n d T a g g e d P MF is a myeloproliferative neoplasm (MPN) in which proinflammatory cytokines derived from malignant cells drive bone marrow fibrosis …

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Measles Reactivity in Windsor Patients Post Autologous Versus Allogeneic Hematopoietic Cell Transplantation: A Retrospective Review

Kayla Elizabeth Negus, Mohammad Jarrar, Indryas Woldie, Sindu Kanjeekal et autres

Background As the antivaccine movement has increased, vaccine preventable illnesses have also increased. The resurgence of measles globally has been noted, specifically the United States received 1200 new cases of measles in 2019, which is the highest number of cases since 1994. …

Measles Reactivity in Windsor Patients Post Autologous Versus Allogeneic Hematopoietic Cell Transplantation: A Retrospective Review

Kayla Elizabeth Negus, Mohammad Jarrar, Indryas Woldie, Sindu Kanjeekal et autres

Background As the antivaccine movement has increased, vaccine preventable illnesses have also increased. The resurgence of measles globally has been noted, specifically the United States received 1200 new cases of measles in 2019, which is the highest number of cases since 1994. …

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Eosinophilia With Hepatic Mass and Abnormal Liver Function Tests: An Unusual Presentation of Chronic Myeloid Leukemia

Neeraja Yerrapotu, Susmitha Edappallath, Mohammad Jarrar, Caroline Hamm et autres

Chronic myeloid leukemia (CML) is a chronic myeloproliferative neoplasm characterized by excess granulocytes at different stages of maturation and the presence of BCR-ABL1 fusion gene or Philadelphia chromosome. Absolute eosinophilia, basophilia, and monocytosis are not uncommon in CML. However, a rare entity …

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Autoimmune Hemolytic Anemia in a 24-Year-Old Patient With COVID-19 Complicated by Secondary Cryptococcemia and Acute Necrotizing Encephalitis: A Case Report and Review of Literature

Indryas Woldie, Ian G. Brown, Nduka Francis Nwadiaro, Amit Patel et autres

Since the initial reported outbreak of coronavirus disease 2019 (COVID-19), many unique case reports have been published in the medical literature. Here we report a complicated clinical course of a young patient with COVID-19 who presented initially with recurrent autoimmune hemolytic anemia …

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Fludarabine, Antithymocyte Globulin and Low Dose Cyclophosphamide As Conditioning Regimen for Allogeneic Stem Cell Transplantation in Children with Severe Aplastic Anemia

Mohammed Essa, Reem Al Sudairy, Sameera Al Afghani, Mohammad Jarrar et autres

There is no standard conditioning regimen for children with severe aplastic anemia (SAA) and short telomeres. Here, we summarize our experience in ten patients with SAA and short (n=6) or undetermined telomeres (n=4) who have been transplanted with HLA-matched related hematopoietic donor …

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Early Stage Triple Negative Breast Cancer Has Significantly Better Outcomes than More Advanced Disease: A Single Centre Retrospective Review

Caroline Hamm, Swati Kulkarni, Rasna Gupta, Amin Kay et autres

A retrospective, serial analysis of 181 triple negative breast cancer (TNBC) patients was undertaken at a regional cancer centre in Canada. The primary focus of the analysis was to investigate the effect of presenting stage in patients with TNBC on progression free …

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Hematopoietic stem cell transplantation practice variation among centers in the Eastern Mediterranean Region (EMRO)

Walid Rasheed, Ardeshir Ghavamzadeh, Rose‐Marie Hamladji, Tarek Ben Othman et autres

INTRODUCTION: This practice survey is conducted to analyze clinical hematopoietic stem cell transplantation (HSCT) practice variability among centers in the WHO Eastern Mediterranean Region (EMRO), as represented by the Eastern Mediterranean Blood and Marrow Transplantation (EMBMT) group. METHOD: This internet based survey …

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Chances of finding a matched parent-child in hematopoietic stem cell transplantation in Saudi Arabia.

Ali H. Hajeer, Manal Algattan, Aisha Anizi, Ahmed Alaskar et autres

Hematopoietic stem cell transplantation (HSCT) is a life-saving procedure used to treat several congenital and malignant diseases. Related matched stem cell donors give better outcome than unrelated donors. However, high-resolution matching for HLA-A, -B, -C, and -DRB1 alleles was found to be …

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