Alessandra Cecchi

Home based early intervention with CareToy-Revised in infants with early brain injury: a randomized controlled trial

Elena Beani, Riccardo Rizzi, Veronica Barzacchi, Valentina Menici et autres

Introduction Intensive, family-centered early intervention (EI) may support neurodevelopment during a period of high neuroplasticity in infants with perinatal brain injury who are at high risk of cerebral palsy (CP). CareToy-Revised (CT-R) is a smart, home-based, parent-delivered system that provides individualized, goal-directed …

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Glucose-to-lactate ratio in infants with hypoxic-ischemic encephalopathy treated with hypothermia

Carlo Dani, Giulia Remaschi, Elia Benelli, Alessandra Cecchi et autres

BACKGROUND: Glucose-to-lactate ratio and abnormal values of glucose and lactate blood values, as well as neuroimaging, have been reported to predict neurodevelopmental outcome in infants with hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH). Our aim was to confirm or confute these …

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Maternal singing and speech have beneficial effects on preterm infant’s general movements at term equivalent age and at 3 months: an RCT

Manuela Filippa, Gianluca Filippa, Elisa Della Casa, Alberto Berardi et autres

Background: General Movements (GMs) are part of the spontaneous movement repertoire and assessing them helps to determine the integrity of the central nervous system in newborns. The aim of this study was to investigate the effects of maternal singing and speaking in …

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Resuscitation With Placental Circulation Intact Compared With Cord Milking

Simone Pratesi, Martina Ciarcià, Luca Boni, Stefano Ghirardello et autres

Importance: Among preterm newborns undergoing resuscitation, delayed cord clamping for 60 seconds is associated with reduced mortality compared with early clamping. However, the effects of longer durations of cord clamping with respiratory support are unknown. Objective: To determine whether resuscitating preterm newborns …

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Lung Recruitment Before Surfactant Administration in Extremely Preterm Neonates

Francesca Gallini, Domenico Umberto De Rose, Roberta Iuliano, Domenico M. Romeo et autres

Importance: A multicenter randomized clinical trial (RCT) showed a lung recruitment maneuver using high-frequency oscillatory ventilation just before surfactant administration (ie, intubate-recruit-surfactant-extubate [IN-REC-SUR-E]) improved the efficacy of treatment compared with the standard intubate-surfactant-extubate (IN-SUR-E) technique without increasing the risk of adverse neonatal …

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Correction: Enteral and Parenteral Treatment with Caffeine for Preterm Infants in the Delivery Room: A Randomised Trial

Carlo Dani, Alessandra Cecchi, Martina Ciarcià, Francesca Miselli et autres

Correction: Enteral and Parenteral Treatment with Cafeine for Preterm Infants in the Delivery Room: A Randomised Trial

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Maternal singing sustains preterm hospitalized newborns’ autonomic nervous system maturation: an RCT

Manuela Filippa, M. Nardelli, Alessandra Sansavini, Sara Meloni et autres

BACKGROUND: Premature birth is known to affect the newborn's autonomic nervous system (ANS) maturation, with potential short and long-term impact on their neurobehavioral development. The purpose of the study was to investigate the effects of maternal directed singing and speaking on the …

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Early vocal contact has beneficial effects on preterm infant’s vagal activity during hospitalization

Manuela Filippa, M. Nardelli, Erika Casa, Alberto Berardi et autres

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Enteral and Parenteral Treatment with Caffeine for Preterm Infants in the Delivery Room: A Randomised Trial

Carlo Dani, Alessandra Cecchi, Martina Ciarcià, Francesca Miselli et autres

BACKGROUND: Early treatment with caffeine in the delivery room (DR) has been proposed to decrease the need for mechanical ventilation (MV) by limiting episodes of apnoea and improving respiratory mechanics in preterm infants. Our aim was to verify the hypothesis that intravenous …

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Maternal Singing but Not Speech Enhances Vagal Activity in Preterm Infants during Hospitalization: Preliminary Results

Manuela Filippa, M. Nardelli, Elisa Della Casa, Alberto Berardi et autres

Background: Early parental interventions in the Neonatal Intensive Care Units (NICUs) have beneficial effects on preterm infants’ short and long-term outcomes. The aim of this study was to investigate the effects of Early Vocal Contact (EVC)—singing and speaking—on preterm infants’ vagal activity …

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Feasibility of Early Intervention Through Home-Based and Parent-Delivered Infant Massage in Infants at High Risk for Cerebral Palsy

Valentina Menici, Camilla Antonelli, Elena Beani, Alessandra Mattiola et autres

Infant massage (IM) can be considered an early intervention program that leads to the environmental enrichment framework. The effectiveness of IM to promote neurodevelopment in preterm infants has been proved, but studies on infants with early brain damage are still lacking. The …

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Resuscitative endovascular occlusion of the aorta (REBOA) for refractory out of hospital cardiac arrest. An Utstein-based case series

Lorenzo Gamberini, Carlo Coniglio, Cristian Lupi, Marco Tartaglione et autres

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