Soji Ozawa

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2021

Katsuhiko Iwakiri, Yasuhiro Fujiwara, Noriaki Manabe, Eikichi Ihara et autres

In Japan, with the increasing prevalence of gastroesophageal reflux disease (GERD) and growing public interest, the Japanese Society of Gastroenterology issued Evidence-based Clinical Practice Guidelines for GERD (1st edition) in 2009 and a revised 2nd edition in 2015. A number of studies …

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Three Resection Cases of Esophageal Gastrointestinal Stromal Tumor Using Different Therapeutic Strategies

Kohei Tajima, Kazuo Koyanagi, Yamato Ninomiya, Kentaro Yatabe et autres

食道gastrointestinal stromal tumor（以下，GISTと略記）の3手術例を経験したので本邦報告例の文献的考察とともに報告する．症例1は51歳の男性で，Fletcher分類の低リスク群GISTに対して，胸腔鏡下食道腫瘍核出術を施行した．症例2は77歳の女性で，経胸腹アプローチでの食道切除と再建が必要と予想されたため，イマチニブによる術前治療後に，経裂孔的下部食道噴門側胃切除術を施行した．症例3は84歳の女性で，GISTの術前診断には至らなかったが，腫瘍は増大傾向であり，臨床上GISTを疑い，経裂孔的下部食道噴門側胃切除を行った．症例1，2のように，低リスク症例への核出術や腫瘍径の大きな症例への術前治療の導入により，侵襲の高い食道切除と再建を回避できる可能性が示唆された．食道GISTの診療において，手術侵襲と根治性を踏まえた最適な治療戦略の選択が求められる．

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Change in Contralateral Muscle Blood Volume During Passive Unilateral Muscle Stretching Before and After Surgery.

Tomoko Kutsuzawa, Hisako Matsumoto, Daisaku Kurita, Satoshi Iwamoto et autres

OBJECTIVE: Passive muscle stretching is a common physical therapy for critically ill patients in the intensive care units. This study aimed to evaluate the effects of unilateral passive stretching of the gastrocnemius muscle (GM) before and after surgery on blood volume (BV) …

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Prediction of non-functioning pancreatic neuroendocrine tumor grades with fractal analysis of preoperative contrast-enhanced computed tomography images

Akira Nakano, Koichi Hayano, Toru Tochigi, Taro Mashiko et autres

PURPOSE: To assess intra-tumoral heterogeneity (ITH) via fractal analysis of preoperative contrast-enhanced computed tomography (CT) images to predict pathological grades in non-functioning pancreatic neuroendocrine tumors (NF-PNETs) and verify its impact on patient survival. METHODS: This retrospective study enrolled 40 patients with NF-PNET …

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Combined primary hepatic neuroendocrine carcinoma and hepatocellular carcinoma: case report and literature review

Akira Nakano, Kenichi Hirabayashi, Hiroshi Yamamuro, Taro Mashiko et autres

BACKGROUND: Hepatocellular carcinoma (HCC) can grow in a mosaic pattern, often combined with various non-hepatocellular cells. However, HCC combined with a neuroendocrine carcinoma (NEC) component is rarely reported, and its clinical features, origin, diagnosis, and behavior have not been established. In the …

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Combined primary hepatic neuroendocrine carcinoma and hepatocellular carcinoma: case report and literature review

Akira Nakano, Kenichi Hirabayashi, Hiroshi Yamamuro, Taro Mashiko et autres

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Adult Ileo-ileal Intussusception Due to Inflammatory Fibroid Polyp: A Case Report.

Taro Mashiko, Naoki Sakoda, Akira Nakano, Yoshihito Masuoka et autres

INTRODUCTION: Intussusception occurs when one part of the intestines slides into the adjacent intestine resulting in bowel obstruction. It is a rare condition in adults, accounting for only 5% of all intussusceptions. It has multiple causes, with inflammatory fibroid polyps (IFPs) very …

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Combined Primary Hepatic Neuroendocrine Carcinoma and Hepatocellular Carcinoma: Case Report and Literature Review

Akira Nakano, Kenichi Hirabayashi, Taro Mashiko, Yoshihito Masuoka et autres

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[Radical Resection of a Locally Advanced Unresectable Pancreatic Adenosquamous Carcinoma after Treatment with Systemic Chemotherapy].

Taro Mashiko, Akira Nakano, Yoshihito Masuoka, Seiichiro Yamamoto et autres

A 64-year-old man visited our hospital because of weight loss and after being detected with a tumor in the pancreatic body and tail on abdominal ultrasonography at a nearby hospital. Abdominal contrast-enhanced CT revealed a 45 mm tumor with celiac artery invasion …

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Role of indocyanine green fluorescence imaging on blood flow evaluation of the reconstructed conduit after esophageal cancer surgery

Kazuo Koyanagi, Soji Ozawa

Argon Plasma Coagulation Treatment for superficial esophageal cancer: A Case Report

Mifuji Tomioku, Hideo Shimada, Takayuki Nishi, Takayuki Tajima et autres

Since lymph node metastases are rare in early esophageal cancer diagnosed as T1a-EP or T1a-LPM, endoscopic resection (ER) has become the standard treatment for these early esophageal cancers. However, a high level of skill is required for ER of extensive and circumferential …

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Regeneration of Transected Recurrent Laryngeal Nerve Using Hybrid-Transplantation of Skeletal Muscle-Derived Stem Cells and Bioabsorbable Scaffold

Akihito Kazuno, Daisuke Maki, Ippei Yamato, Nobuyuki Nakajima et autres

Hybrid transplantation of skeletal muscle-derived multipotent stem cells (Sk-MSCs) and bioabsorbable polyglyconate (PGA) felt was studied as a novel regeneration therapy for the transected recurrent laryngeal nerve (RLN). Sk-MSCs were isolated from green fluorescence protein transgenic mice and then expanded and transplanted …

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