José María Fernández‐Rañada

Real-World Experience with Daratumumab Maintenance After ASCT in Newly Diagnosed Multiple Myeloma (NDMM): Preliminary Data From a Single-Center

Carmen Martínez Chamorro, Aránzazu Alonso Alonso, Concepción Aláez Usón, Virginia Pradillo Fernández et autres

P-215: D-VTd as induction therapy in newly diagnosed multiple myeloma (NDMM) patients who are candidates for transplantation: a real-life experience in a single center

Carmen Martínez Chamorro, Arancha Alonso Alonso, Concepción Aláez Usón, Virginia Pradillo Fernández et autres

Dose‐escalated CHOP and tailored intensification with IFE according to early response and followed by BEAM/autologous stem‐cell transplantation in poor‐risk aggressive B‐cell lymphoma: a prospective study from the GEL–TAMO Study Group

Reyes Arranz, Eulogio Conde, Carlos Grande, María‐Victoria Mateos et autres

OBJECTIVES: The role of high-dose therapy and autologous stem-cell transplantation (HDT/ASCT) in the up-front treatment of poor-risk aggressive lymphoma is still unknown. We conducted a prospective multi-centre trial with dose-escalated CHOP (MegaCHOP) and tailored intensification prior to HDT/ASCT according to early response …

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Idiopathic Cytopenia of Undetermined Significance (ICUS): Impact of Flow Cytometry Immunophenotyping (FCI) in the Diagnosis of Myelodysplastic Syndrome (MDS) When Morphology Is Not Conclusive.

Patricia Font, Dolores Subirá, Javier Loscertales, Eva Arranz et autres

Abstract Introduction: Morphology and cytogenetics are the basis for the study of MDS, however sometimes it is difficult to establish this diagnosis. The term ICUS was recently proposed (Mufti, 2005) for cases with persistent idiophatic cytopenia without evidence of dysplasia in the …

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Impact of cytogenetics on outcome of patients with MDS or secondary AML undergoing allogeneic HSCT from HLA-Identical siblings

Francesco Onida, Ronald Brand, Anja van Biezen, Renée M. Y. Barge et autres

Impact of Cytogenetics on Outcome of Patients with MDS or Secondary AML Undergoing Allogeneic HSCT from HLA-Identical Siblings: A Retrospective Analysis of the EBMT-CLWP.

Francesco Onida, Ronald Brand, Anja van Biezen, Renée M. Y. Barge et autres

Abstract Cytogenetics (CG) represent one of the most important factors in determining survival for pts with MDS, being therefore required by the IPSS to predict life-expectancy. However, the impact of CG on outcome of pts undergoing allo-HSCT for MDS is unknown. The …

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Cisplatin-Based Protocols as Salvage Therapy for Relapsed or Refractory Hodgkin’s Lymphoma Patients.

Iván Alvarez, Anna Sureda, Reyes Arranz, Raúl Córdoba et autres

Abstract We have analyzed the results in terms of response rate and peripheral blood progenitor cell (PBPC) mobilization ability of two cisplatin-based chemotherapy salvage regimens [DHAP (cisplatin 100 mg/m2 iv day 1, ara-c 4 g/m2 iv day 2 and dexamethasone 40 mg …

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Phenotypic Aberrations of Myeloid CD34+ Cells in Patients with Myelodysplastic Syndrome (MDS): Clinical Significance and Correlation with Cytogenetics Abnormalities.

Dolores Subirá, Patricia Font, Eva Arranz, Ramiro B Soraya et autres

Abstract Expression of abnormal markers in myeloid CD34+ cells of patients with MDS is common, but few immunophenotypic data have been compiled so far. Based on the statement that CD7 and TdT are markers associated with a bad prognosis in acute myeloid …

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Flow Cytometry Applications in the Diagnosis of Myelodysplastic Syndrome (MDS): Analysis of 45 Cases.

Patricia Font, Dolores Subirá, Maria C. Martinez-Chamorro, Susana Castañón et autres

Abstract Flow cytometry is a widely used method to study most of the hematologic malignancies. The utility of bone marrow immunophenotyping for the evaluation of patients with myelodisplastic syndrome (MDS) is currently being evaluated but most of these studies are based on …

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Mixedema grave como causa de transformación gelatinosa de la médula ósea reversible tras tratamiento tiroideo sustitutivo

Juan José Gil‐Fernández, Ana Teresa Tamayo Martín, José María Fernández‐Rañada

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Mixedema grave como causa de transformación gelatinosa de la médula ósea reversible tras tratamiento tiroideo sustitutivo

Juan José Gil‐Fernández, Ana Teresa Tamayo Martín, José María Fernández‐Rañada

Chemokine receptors that mediate B cell homing to secondary lymphoid tissues are highly expressed in B cell chronic lymphocytic leukemia and non-Hodgkin lymphomas with widespread nodular dissemination

Sonia López-Giral, Nuria Quintana, María Cabrerizo, Manuel Alfonso-Pérez et autres

B cell neoplasms present heterogeneous patterns of lymphoid organ involvement, which may be a result of the differential expression of chemokine receptors. We found that chemokine receptor (CCR)7, CXC chemokine receptor (CXCR)4, or CXCR5, the main chemokine receptors that mediate B cell …

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