Sergey A. Siletsky

Editorial: Exploration of the role of heme proteins in biology with experimental and computational methods

Dragan M. Popović, Sergey A. Siletsky, Chunmao He, M. R. Gunner

Studying how these biomolecules function can help design more efficient drugs or inhibitors and develop more effective treatments for disorders related to the clinically relevant mutations and dysfunction of heme proteins (Zhai et al., 2023;Lee et al., 2024). Synthetic bioinspired heme proteins …

rs, ru, cn, us (code pays fourni par la source)

Special Issue “Ion Pumps: Molecular Mechanisms, Structure, Physiology”

Sergey A. Siletsky

This Special Issue, entitled "Ion Pumps: Molecular Mechanisms, Structure, and Physiology," is devoted to studies of membrane proteins that transport ions [...].

ru (code pays fourni par la source)

Mechanisms of inward transmembrane proton translocation

Kirill Kovalev, Fedor M. Tsybrov, Alexey A. Alekseev, Vitaly Shevchenko et autres

de, ru, fr, es (code pays fourni par la source)

Proton Pumps: Molecular Mechanisms, Inhibitors and Activators of Proton Pumping

Sergey A. Siletsky

Protein molecular machines, also known as proton pumps, are the most important element of biological membranes [...].

ru (code pays fourni par la source)

Mirror proteorhodopsins

Ivan S. Okhrimenko, Kirill Kovalev, Lada E. Petrovskaya, Nikolay S. Ilyinsky et autres

Proteorhodopsins (PRs), bacterial light-driven outward proton pumps comprise the first discovered and largest family of rhodopsins, they play a significant role in life on the Earth. A big remaining mystery was that up-to-date there was no described bacterial rhodopsins pumping protons at …

ru, de, nl, fr (code pays fourni par la source)

Oriented Insertion of ESR-Containing Hybrid Proteins in Proteoliposomes

Lada E. Petrovskaya, Evgeniy P. Lukashev, Mahir D. Mamedov, Elena A. Kryukova et autres

Microbial rhodopsins comprise a diverse family of retinal-containing membrane proteins that convert absorbed light energy to transmembrane ion transport or sensory signals. Incorporation of these proteins in proteoliposomes allows their properties to be studied in a native-like environment; however, unidirectional protein orientation …

ru, us (code pays fourni par la source)

Application of direct electrometry in studies of microbial rhodopsins reconstituted in proteoliposomes

Sergey A. Siletsky, Mahir D. Mamedov, Evgeniy P. Lukashev, Sergei P. Balashov et autres

ru, us (code pays fourni par la source)

Proton transfer reactions in donor site mutants of ESR, a retinal protein from Exiguobacterium sibiricum

Lada E. Petrovskaya, Evgeniy P. Lukashev, Sergey A. Siletsky, Eleonora S. Imasheva et autres

ru, us (code pays fourni par la source)

Electrophysiological Characterization of Microbial Rhodopsin Transport Properties: Electrometric and ΔpH Measurements Using Planar Lipid Bilayer, Collodion Film, and Fluorescent Probe Approaches

Tatyana I. Rokitskaya, Nina L. Maliar, Sergey A. Siletsky, Valentin Gordeliy et autres

ru, fr (code pays fourni par la source)

Proton Pumping and Non-Pumping Terminal Respiratory Oxidases: Active Sites Intermediates of These Molecular Machines and Their Derivatives

Sergey A. Siletsky, Vitaliy B. Borisov

Terminal respiratory oxidases are highly efficient molecular machines. These most important bioenergetic membrane enzymes transform the energy of chemical bonds released during the transfer of electrons along the respiratory chains of eukaryotes and prokaryotes from cytochromes or quinols to molecular oxygen into …

ru (code pays fourni par la source)

ROS Defense Systems and Terminal Oxidases in Bacteria

Vitaliy B. Borisov, Sergey A. Siletsky, Martina R. Nastasi, Elena Forte

Reactive oxygen species (ROS) comprise the superoxide anion (O2•−), hydrogen peroxide (H2O2), hydroxyl radical (•OH), and singlet oxygen (1O2). ROS can damage a variety of macromolecules, including DNA, RNA, proteins, and lipids, and compromise cell viability. To prevent or reduce ROS-induced oxidative …

ru, it (code pays fourni par la source)

Specific inhibition of proton pumping by the T315V mutation in the K channel of cytochrome ba3 from Thermus thermophilus

Sergey A. Siletsky, Tewfik Soulimane, Ilya N Belevich, Robert B. Gennis et autres

ru, ie, fi, us (code pays fourni par la source)