F.J.G. van der Ouderaa

Abstracts of Papers Presented at the 34th ORCA Congress (Part 2 of 3)

H. Duschner, H. Uchtmann, Hugo De Bruyn, L.J. Van Rijn et autres

The Effect of Chlorhexidine and Zinc/Triclosan Mouthrinses on the Production of Acids in Dental Plaque

J.S. van der Hoeven, Donna R. Cummins, M.J.M. Schaeken, F.J.G. van der Ouderaa

Chlorhexidine, and zinc in combination with triclosan, are used as anti-plaque agents in the prevention of gingivitis. The multifunctional activity of these compounds against bacterial cells has been proposed to include interference with sugar transport and reduction of glycolysis. In this study …

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Acknowledgements

Adrian Lussi, Alan Trevor Linde, Hitoshi Tsuda, Jan Willem Arends et autres

Inhibition of Acid Production by Streptococcus mutans NCTC 10449 by Zinc and the Effect of Metal Speciation

G.K. Watson, Donna R. Cummins, F.J.G. van der Ouderaa

Ionic zinc as zinc sulphate was strongly inhibitory to acid production from glucose by washed cell suspensions of Streptococcus mutans NCTC 10449 in a pH-stat assay (50% inhibition at 0.1 mM zinc). Zinc was adsorbed to the cells (up to 8 micrograms/mg …

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Oral Disposition of Triclosan (2,4,4′-Trichloro-2′-Hydroxydiphenyl Ether) Delivered from a Dentifrice

Robert J.C. Gilbert, S.B. Fraser, F.J.G. van der Ouderaa

This paper reports measurements of oral retention and intra-oral distribution of triclosan in man after use of an antiplaque toothpaste slurry containing this antibacterial. Determinations of triclosan were made by high-performance liquid chromatography. It was shown that 38% of the triclosan in …

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Long-Term Exposure of Plaque to Zinc Citrate

Carolyn Jones, K.W. Stephen, Jennifer Ritchie, E. Huntington et autres

The effect of 3 years’ continuous exposure to dentifrices containing different levels of sodium monofluorophosphate, with or without 0.5% zinc citrate, has been investigated on plaque growth inhibition. Additionally, changes in the plaque microflora during prolonged exposure to zinc have been monitored …

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Contents, Vol. 25, 1991

Joop de Vries, Jan L. Ruben, Lee Chow, Shozo Takagi et autres

Author Index

Joop de Vries, J. Ruben, Lee Chow, Shozo Takagi et autres

Announcements

Harry Reintsema, Jan Willem Arends, Vera Caslavska, P. Grøn et autres

Acknowledgement to Referees

Harry Reintsema, Johannes Arends, Vera Caslavska, P. Grøn et autres

Anti‐plaque agents. Rationale and prospects for prevention of gingivitis and periodontal disease

F.J.G. van der Ouderaa

Abstract. Oral health surveys have shown that even in countries with established patterns of oral hygiene habits, most individuals have relatively poor gingival health. This is due to a low interest in complying with oral health procedures. A number of factors are …

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The effect of a dentifrice containing zinc citrate and Triclosan on developing gingivitis

C.A. Saxton, F.J.G. van der Ouderaa

A partial mouth experimental gingivitis model was employed to establish the potential efficacy of a dentifrice containing a zinc salt and the antimicrobial agent Triclosan to prevent or delay the development of gingivitis over a period of 28 days. Initially, gingival health …

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