Brendan F. Murphy

Whither medicine? The expansion of non‐doctor practice

Brendan F. Murphy

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Renovascular Hypertension: Treatment with the Oral Angiotensin-Converting Enzyme Inhibitor Enalapril

Bruce Jackson, Brendan F. Murphy, Colin I. Johnston, Priscilla Kincaid‐Smith et autres

Sixteen patients with an established diagnosis of renovascular hypertension were entered in an open study of enalapril (MK421), an oral angiotensin-converting enzyme (ACE) inhibitor, for treatment of their hypertension. Initial blood pressure was 178.9 +/- 6.3/106.2 +/- 3.1 mm Hg during conventional …

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Quiz of the Month, Answer

Shane L. Carney, Trefor Owen Morgan, Stanley Goldfarb, Zalman S. Agus et autres

Errata

Geert L. M. van Rens, A.H.M. Geurts van Kessel, Haiko J. Bloemendal, Timothy.A. Donlon et autres

Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease)

Maria Asuncion Abrera-Abeleda, Carla J. Nishimura, Jenna L.H. Smith, Sanjjev Sethi et autres

INTRODUCTION: Membranoproliferative glomerulonephritis type II or dense deposit disease (MPGN II/DDD) causes chronic renal dysfunction that progresses to end stage renal disease in about half of patients within 10 years of diagnosis. Deficiency of and mutations in the complement factor H (CFH) …

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Human Factor H-Related Protein 5 Has Cofactor Activity, Inhibits C3 Convertase Activity, Binds Heparin and C-Reactive Protein, and Associates with Lipoprotein

Jennifer L. McRae, Thomas G. Duthy, Kim M. Griggs, Rebecca J. Ormsby et autres

Factor H-related protein 5 (FHR-5) is a recently discovered member of the factor H (fH)-related protein family. FHR proteins are structurally similar to the complement regulator fH, but their biological functions remain poorly defined. FHR-5 is synthesized in the liver and consists …

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Treatment of acute renal failure caused by renal artery occlusion with renal artery angioplasty

Karen M. Dwyer, John Ioannis Vrazas, Robert S. Lodge, Timothy J. Humphery et autres

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Location and Structure of the Human FHR-5 Gene

Jennifer L. McRae, Brendan F. Murphy, Helen J. Eyre, Grant R. Sutherland et autres

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Membranoproliferative glomerulonephritis in association with chronic lymphocytic leukaemia: a report of three cases

Prudence A. Hill, Frank Caleb Firkin, Karen M. Dwyer, Petrova Lee et autres

au, us (code pays fourni par la source)

Nocardia peritonitis and abdominal abscess complicating continuous ambulatory peritoneal dialysis

Karen M. Dwyer, John R. Daffy, Brendan F. Murphy

SUMMARY: Peritonitis is a common problem in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and represents the most frequent cause of peritoneal catheter loss and discontinuation of CAPD. The incidence of peritonitis remains less than one episode per patient year of treatment. …

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Human Factor H-related Protein 5 (FHR-5)

Jennifer L. McRae, Peter J. Cowan, David A. Power, Ken I. Mitchelhill et autres

A novel human plasma protein has been identified as a universal component of complement deposits, when complement is detected immunohistochemically in vivo. The protein is homologous to complement factor H and related proteins and has been designated factor H-related protein 5 (FHR-5). …

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Sublytic Complement Injury Does Not Activate NF-κB, or Induce Mitogenesis in Rat Mesangial Cells

S. J. Mudge, Jennifer L. McRae, Russell B. Auwardt, Brendan F. Murphy et autres

Sublytic complement injury to glomerular mesangial cells, mediated by the terminal membrane attack complex of complement (C5b-9), is a potential initiating mechanism in IgA nephropathy. Sublytic complement injury has been reported to result in the production of a variety of pro-inflammatory molecules …

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