Francis Michael Clarke

Evaluation of LDL and HDL subclasses in patients with dyslipidaemia

Michael Eamon Kelly, S. Mc Girl, Gerard P Boran, Vincent M. G. Maher et autres

ie (code pays fourni par la source)

The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project

Lawrence N. Hudson, Tim Newbold, Sara Contu, Samantha L. L. Hill et autres

The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land …

gb, de, ca, be, Ghana, cr, ar, es, ph, fr, my, au, co, mx, uy, Côte d’Ivoire, hu, us, br, nz, pt, lt, pa, ch, se, in, gy, Cameroun, nl, ie (code pays fourni par la source)

The 2016 release of the PREDICTS database [SUPERSEDED]

Lawrence N. Hudson, Tim Newbold, Sara Contu, Samantha L. L. Hill et autres

__IMPORTANT NOTICE: THIS VERSION OF THE DATABASE HAS BEEN SUPERSEDED__ Data review in 2021-2023 has resulted in some changes and additions to the database. The new version (version 1.1), is available for non-commercial use [https://data.nhm.ac.uk/dataset/the-2016-release-of-the-predicts-database-v1-1]. A dataset of 3,250,404 measurements, collated from …

Developing and promoting student discussion capacity in the classroom

Mary Gregory, Martin Bridgstock, Francis Michael Clarke

The art of conversing competently in scientific language that translates content into every day context is an important graduate skill that is not necessarily inherent but can be developed. Within our undergraduate programs there are a number of courses that implement modifications …

Cementing Core Concepts with Crafty Constructions

Mary Gregory, Francis Michael Clarke

Second year Metabolism and third year Immunology at Griffith University are subjects where a concrete understanding of central concepts is imperative to mastering the complex mechanisms and pathways these topics encompass. The use of traditional teaching methods frequently leaves students seemly unable …

Hypoxic and redox signaling pathways interact to maintain oxygen homeostasis

Therese Karlenius, Fenil Shah, Jenny Di Trapani, Francis Michael Clarke et autres

The dynamic relationship between oxygen levels within a cell leads to the activation of various signaling pathways to maintain homeostasis. If levels are low then hypoxic stress occurs and the classical hypoxia-signaling pathway via HIF-1 is activated. If oxidative stress occurs then …

Characterisation of Novel Thioredoxin Dimers.

Leisa Jane Osborne, Jenny Di Trapani, Kathryn Fay Tonissen, Francis Michael Clarke

Griffith Sciences, Griffith Institute for Drug Discovery

Fluorescence-Activated Cell Sorting analysis of Thioredoxin in cancer cells under different oxygen conditions

Fenil Shah, Jenny Di Trapani, Therese Karlenius, Francis Michael Clarke et autres

Thioredoxin is a redox capable protein that is integral to the functioning of cells. It performs several roles within the intracellular environment, including the scavenging of reactive oxygen species or ROS. Oxidative stress is caused when the cell contains excessive levels of …

Expression and regulation of Thioredoxin in cancer cells during hypoxia

Therese Karlenius, Fenil Shah, Francis Michael Clarke, Kathryn Fay Tonissen

Redox homeostasis is crucial for cell survival. Too much oxygen in the cell leads to oxidative stress through the production of ROS, which reacts with the cells macromolecules causing cell damage and finally cell death. The cells defend themselves against oxidative stress …

Investigating the effect of hypoxia on antioxidants in cancer cells.

Therese Karlenius, Fenil Shah, Francis Michael Clarke, Kathryn Fay Tonissen

No Full Text

Identifying binding partners for thioredoxin in the intracellular and extracellular cancer cell environment

Fenil Shah, Therese Karlenius, Francis Michael Clarke, Kathryn Fay Tonissen

Griffith Sciences, School of Natural Sciences

Complex regulation of the human thioredoxin gene promoter

Simone A. Osborne, Hye-Jin Kim Hawkes, Benjamin Lyle Baldwin, Francis Michael Clarke et autres

No Full Text