Steven Nagel

Pregnancy-Associated Breast Cancer: A Trimester and Subtype Based Clinical Decision Framework for the Surgeon and Surgical Trainee

Hemanth Venkatesh, Gabriela Castro Gierach, Lauren Kanzaki, Ahmed Ali et autres

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A rare BRCA1 alternative missense mutation identified in African American women with breast cancer

Desta Beyene, Luisel Ricks‐Santi, Delisha A. Stewart, Muneer Abbas et autres

Introduction: Hereditary breast cancer is most commonly caused by inherited mutations in the BRCA1 or BRCA2 genes, which significantly increase the risk of breast and ovarian cancers. Methods: Denaturing High-Performance Liquid Chromatography (DHPLC) and DNA sequencing were used to analyze BRCA1 mutations, …

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Opportunities for Pragmatic Design Elements in Surgical Trials

Ali Abbasi, Adam S. Weltz, Donna R. Rivera, Steven Nagel et autres

Importance: Randomized clinical trials (RCTs), the gold standard of medical evidence, remain relatively rare in surgery. In part, this is the result of challenges that are unique to surgical trials, including surgeon concerns about lack of equipoise, slow recruitment, difficulty standardizing interventions, …

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Abstract P5-01-18: ESRα and RASSF1A promoter methylation changed significantly in benign tumors and in the early event of breast cancer progression

Yasmine Kanaan, Sylvia Dasi, Bernard Kwabi‐Addo, Desta Beyene et autres

Abstract Methylation in the estrogen receptor alpha (ESRa) promoter is an epigenetic abnormality in breast cancer (BCa) and hypermethylation-mediated loss of ESRa expression could provide the cell with growth-promoting characteristics such as insensitivity to antigrowth signals. To investigate if there is a …

Innovation in Breast Surgery: Practical and Ethical Considerations

Paige Teller, Toan T. Nguyen, Jennifer F. Tseng, Lisa Allen et autres

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13 Breast Implant–Associated Anaplastic Large Cell Lymphoma

Binita S. Ashar, Sung Woon Yoon, Steven Nagel

Breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) is a rare peripheral T-cell lymphoma that develops after placement of breast implants for cosmetic or reconstructive purposes. BIA-ALCL most commonly follows a fairly indolent course, with excellent prognosis in early-stage disease but disseminated cancer …

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Deconfounding the Effects of Cu and Cr on Perceived Fe Contamination in Si Using an SPV Technique

Steven Nagel

The effects of iron, copper, and chrome on minority carrier diffusion length measurements in p type, boron doped, silicon were investigated using a surface photovoltage (SPV) technique. Attempts were made to reproduce previous results for iron and chrome, metals which form complexes …

Cytogenetic studies in a case of Muir-Torre syndrome

Xiao Han, Steven Nagel, Lemuel Herrera, Surabhi Kakati