Accès ouvert
2023
other
OpenAlex
Anita R. Iskandar, Benchun Miao, Xinli Li, Kang‐Quan Hu et autres
Abstract Despite the consistent association between a higher intake of the provitamin A carotenoid β-cryptoxanthin (BCX) and a lower risk of lung cancer among smokers, potential mechanisms supporting BCX as a chemopreventive agent are needed. We first examined the effects of BCX …
Accès ouvert
2023
other
OpenAlex
Anita R. Iskandar, Benchun Miao, Xinli Li, Kang‐Quan Hu et autres
Abstract Despite the consistent association between a higher intake of the provitamin A carotenoid β-cryptoxanthin (BCX) and a lower risk of lung cancer among smokers, potential mechanisms supporting BCX as a chemopreventive agent are needed. We first examined the effects of BCX …
Accès ouvert
2023
other
OpenAlex
Anita R. Iskandar, Benchun Miao, Xinli Li, Kang‐Quan Hu et autres
Supplementary Figure S1. Reduction of mRNA expressions of α7-nachr by BCX supplementation, not α3-, α5-, and β4-nachr, was associated with lung tumor multiplicity. Upper panel: The statistically significant correlation between lung tumor multiplicity (tumor number) and the expression of nachr-α7 mRNA (P …
Accès ouvert
2023
other
OpenAlex
Anita R. Iskandar, Benchun Miao, Xinli Li, Kang‐Quan Hu et autres
Supplementary Figure S1. Reduction of mRNA expressions of α7-nachr by BCX supplementation, not α3-, α5-, and β4-nachr, was associated with lung tumor multiplicity. Upper panel: The statistically significant correlation between lung tumor multiplicity (tumor number) and the expression of nachr-α7 mRNA (P …
Accès ouvert
2023
supplementary-materials
OpenAlex
Anita R. Iskandar, Chun Liu, Donald Eugene Smith, Kang‐Quan Hu et autres
PDF file - 78K, Means body weight of mice
Accès ouvert
2023
supplementary-materials
OpenAlex
Anita R. Iskandar, Chun Liu, Donald E. Smith, Kang‐Quan Hu et autres
PDF file - 69K, The primer sequences for quantitative real-time PCR
Accès ouvert
2023
supplementary-materials
OpenAlex
Blanche C. Ip, Kang‐Quan Hu, Chun Liu, Donald E. Smith et autres
PDF file - 48K, Supplementary Figure S1. Chemical structure of lycopene, APO10LA, acyclic retinoic acid and all-trans retinoic acid.
Accès ouvert
2023
supplementary-materials
OpenAlex
Blanche C. Ip, Kang‐Quan Hu, Chun Liu, Donald E. Smith et autres
PDF file - 54K
Accès ouvert
2023
supplementary-materials
OpenAlex
Blanche C. Ip, Kang‐Quan Hu, Chun Liu, Donald Eugene Smith et autres
PDF file - 44K, Supplementary Table S2. Primer sequences for RT-PCR.
Accès ouvert
2023
supplementary-materials
OpenAlex
Blanche C. Ip, Kang‐Quan Hu, Chun Liu, Donald E. Smith et autres
PDF file - 30K, Supplementary Table S1. High-fat diet composition.
Accès ouvert
2023
supplementary-materials
OpenAlex
Blanche C. Ip, Kang‐Quan Hu, Chun Liu, Donald Eugene Smith et autres
PDF file - 61K, Supplementary Figure S2. Inhibition of carcinogen-initiated (DEN), HFD-promoted glucose intolerance by APO10LA. Glucose tolerance test was conducted on 6-8 mice/group and calculated for AUC.
Accès ouvert
2023
other
OpenAlex
Blanche C. Ip, Kang‐Quan Hu, Chun Liu, Donald E. Smith et autres
Abstract Obesity is associated with increased risk in hepatocellular carcinoma (HCC) development and mortality. An important disease control strategy is the prevention of obesity-related hepatic inflammation and tumorigenesis by dietary means. Here, we report that apo-10′-lycopenoic acid (APO10LA), a cleavage metabolite of …