Mengru Xu

Investigations on the variations of phase compositions and catalytic performance of Al3+-added Cs2AgInCl6 and Cs2AgBiCl6 double perovskite

Yaran Wen, Yani Yao, Haichuan Bian, Yudong Xu et autres

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Genetic variations for bean color of duck beak revealed by genome‐wide association study

Jingjing Qi, Qian Hu, Yang Xi, Yang Zhao et autres

The beak bean, found only in waterfowl and Galliformes, aids in foraging, self-defense and pecking hard objects. Its rich coloration results from prolonged evolutionary adaptation. This study analyzed beak bean phenotypes of duck at 10, 20, 30 and 40 days of age, …

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Mapping multitissue regulatory variants reveals a liver-centric coexpression network associated with duck egg-laying performance

Xi Yang, Jingjing Qi, Yang Zhao, Yutian Zeng et autres

Poultry egg production is shaped by the intertwined action of multiple physiological systems, greatly magnifying the complexity of its underlying genetic regulation. Although multitissue mapping of regulatory variants offers a powerful route to untangle this complexity, comprehensive data sets in ducks remain …

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Coronary microvascular dysfunction: a review of its association with extracardiac organ pathologies

Yuting Duan, Jia Liu, Shan Wang, Tongxiao Luan et autres

Coronary microvascular dysfunction (CMD) is a high-risk factor for numerous cardiovascular events, and there is an increasing focus on the diagnosis and treatment of CMD itself or its association with cardiovascular diseases. However, some evidences suggest potential associations between CMD and multiple …

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Construction of a prediction model for sarcopenic obesity based on machine learning

Mengru Xu, Jia Liu, Song Hu, Tongxiao Luan et autres

Background: In the context of the rapidly aging global population, sarcopenic obesity (SO) in older adults is associated with significantly higher rates of disability and mortality. SO has become a serious and critical public health concern. This study aimed to develop and …

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Sodium butyrate attenuates lipid metabolism disorder via improving mitochondrial function and activating autophagy in LMH cells

Sasa Miao, Mengru Xu, Fang Liu, Xin Dong et autres

Hepatic steatosis is the main characteristic in fatty liver hemorrhagic syndrome (FLHS), sodium butyrate (NaB) has been shown to modulate hepatic metabolism, alleviate oxidative stress and restore mitochondrial function. However, the effects of NaB on avian cellular models have yet to be …

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Branched-chain amino acids induce hyperammonemia via gut-liver axis-mediated ammonia overproduction in laying hens

Huafeng Jian, Mengru Xu, Fang Liu, Libo Zhang et autres

Gut microbiota not only biosynthesizes branched-chain amino acids (BCAA) but also catabolizes and utilizes them, while the effects of dietary BCAA supplementation on intestinal microbiota and metabolism remain largely elusive. Therefore, the present study aimed to investigate the impacts of dietary BCAA …

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Juvenile hormone interacts with insulin and potentiates the ERK signaling pathway for female reproduction in locusts

Lunjie Li, Libin Yang, Guoqing Yu, Lijun Liu et autres

Integrated Transcriptome and Metabolome Analysis Reveals Candidate Genes and Regulatory Pathways Shaping Duck Meat Color

Shuaixue Jiang, Yang Zhao, Yinjuan Lu, Tao Zhang et autres

Meat color is the most intuitive measure of meat quality and has a significant impact on consumer preference. To explore the molecular mechanisms affecting duck pectoralis meat color, the phenotypic traits of Cherry Valley duck (CV, eight males and eight females) and …

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An mRNA expression atlas for the duck with public RNA-seq datasets

Qiuyu Tao, Anqi Huang, Jingjing Qi, Yang Zhao et autres

BACKGROUND: Ducks are globally important poultry species and a major source of farm animal products, including meat, eggs, and feathers. A thorough understanding of the functional genomic and transcriptomic sequences is crucial for improving production efficiency. RESULT: This study constructed the largest …

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Gravitational distribution of regional intrapulmonary shunt assessed by EIT in ARDS

Mengru Xu, Yi Chi, Siyi Yuan, Yelin Gao et autres

Regional ventilation/perfusion (V/Q) mismatch in intrapulmonary shunt in dependent regions has always been considered a hallmark of ARDS. However, little is known about the spatial distribution of shunt, and a clear definition has been lacking. The aim of the study was to …

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Exploration and comparison of the effectiveness of swarm intelligence algorithm in early identification of cardiovascular disease

Tiantian Bai, Mengru Xu, Taotao Zhang, Xianjie Jia et autres

Due to the aging of the global population and lifestyle changes, cardiovascular disease has become the leading cause of death worldwide, causing serious public health problems and economic pressures. Early and accurate prediction of cardiovascular disease is crucial to reducing morbidity and …

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