Rebecca Whitney

Add-On Treatment With Zilebesiran for Inadequately Controlled Hypertension

Akshay S. Desai, Adam D. Karns, Jolita Badarienė, Ahmad Aswad et autres

Importance: In prior monotherapy studies of patients with hypertension, single subcutaneous doses of zilebesiran, an investigational RNA interference therapeutic, reduced serum angiotensinogen levels and systolic blood pressure (SBP) at 3 and 6 months. Objective: To evaluate the efficacy and safety of zilebesiran …

us, lt, gb (code pays fourni par la source)

RNA Interference With Zilebesiran for Mild to Moderate Hypertension

George L. Bakris, Manish Saxena, Anil Gupta, Fadi M. Chalhoub et autres

Importance: Angiotensinogen is the most upstream precursor of the renin-angiotensin-aldosterone system, a key pathway in blood pressure (BP) regulation. Zilebesiran, an investigational RNA interference therapeutic, targets hepatic angiotensinogen synthesis. Objective: To evaluate antihypertensive efficacy and safety of different zilebesiran dosing regimens. Design, …

us, gb (code pays fourni par la source)

Aggression and motivation to disperse in eusocial naked mole-rats, Heterocephalus glaber

Ilapreet Toor, Phoebe D. Edwards, Nagham Kaka, Rebecca Whitney et autres

ca (code pays fourni par la source)