S. C. Basak

Requirements on the gain calibration for LiteBIRD polarisation data with blind component separation

F. Carralot, A. Carones, N Krachmalnicoff, T. Ghigna et autres

Future cosmic microwave background (CMB) experiments are primarily targeting a detection of the primordial $B$-mode polarisation. The faintness of this signal requires exquisite control of systematic effects which may bias the measurements. In this work, we derive requirements on the relative calibration …

no, fr, jp (code pays fourni par la source)

A Bioinformatics Protocol for Rational Design of Peptide Vaccines and the COVID-19 Rampage

Ashesh Nandy, S. C. Basak, Smarajit Manna

The currently ongoing coronavirus pandemic, the SARSCOV- 2, interchangeably referred to as the COVID-19 infection, has in a short span of time altered the ways and means of almost all of mankind. So strong has been its effect that all human activity …

in, us (code pays fourni par la source)

Identification and computational analysis of mutations in SARS-CoV-2

Tathagata Dey, Shreyans Chatterjee, Smarajit Manna, Ashesh Nandy et autres

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2D Polar Co-ordinate Representation of Amino Acid Sequences With some applications to Ebola virus, SARS and SARS-CoV-2 (COVID-19)

Tathagata Dey, Subhamoy Biswas, Shreyans Chatterjee, Smarajit Manna et autres

We consider a novel approach to mathematically define a graphing method to represent amino acid sequences of proteins in two-dimensional plane and characterize them numerically. The amino acids are represented by their relative magnitude of their hydrophobicity. Each amino acid is compared …

in, us (code pays fourni par la source)

A preliminary assessment of the differences between the Malaysian and Bangladesh strains of the highly lethal Nipah virus

Ashesh Nandy, Proyasha Roy, Sumanta Dey, Tathagata Dutta et autres

The recent emergence of a highly lethal zoonotic virus, the Nipah virus, has raised concerns of a possible pandemic with high fatality ratios. While the similarities of the Malaysian and Bangladesh strains of the virus have been commented upon by various authors, …

in, us (code pays fourni par la source)

A brief account of the search for peptide vaccines

Ashesh Nandy, S. C. Basak

An increasing trend of viral diseases have led to search for faster response systems for preventives and therapeutics. While traditional vaccinations have led to spectacular successes against smallpox and polio viruses, the need for rapid response to new viral epidemics, like in …

in, us (code pays fourni par la source)

Some Comments on Mathematical Descriptors of Biomolecular Sequences and their Characteristics

Ashesh Nandy, S. C. Basak

The advent of techniques of graphical representation and mathematical characterization of biomolecular sequences has seen the growth of a genre of non-alignment methods for analyses of their similarities/dissimilarities. The new descriptors are important and convenient to provide a quantitative measure of the …

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Comparison of Base Distributions in Dengue, Zika and Other Flavivirus Envelope and NS5 Genes

Ashesh Nandy, Sumanta Dey, Proyasha Roy, S. C. Basak et autres

Among the nucleotide sequences of flaviviruses that include Zika virus, Dengue virus, yellow fever virus, Japanese encephalitis virus and West Nile virus, those of the Zika virus and Dengue type 2 virus are believed to share a high degree of similarity as …

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Interdependence of Influenza HA and NA and possibilities of new reassortments

Ashesh Nandy, S. C. Basak

The influenza virion is characterized by two surface proteins, hemagglutinin (HA) and neuraminidase (NA). The changes in their surface antigenic sites have given rise to several subtypes – H1 to H16 for the hemagglutinin and N1 to N9 for the neuraminidase, and …

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Novel Approach for the Numerical Characterization of Molecular Chirality.

Ramanathan Natarajan, S. C. Basak, Terence S. Neumann

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

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Similarity and Dissimilarity of DNA∕RNA Sequences

Dorota Bielińska-Wąż, Piotr Wąż, Wiesław Nowak, Ashesh Nandy et autres

Multi‐dimensional aspects of similarity studies of DNA/RNA sequences are emphasized. The new graphical representation presented in our recent papers and its descriptors are used as numerical examples of the multi‐dimensionality.

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A quantitative structure–activity relationship (QSAR) study of dermal absorption using theoretical molecular descriptors

S. C. Basak, Denise Mills, Moiz Mumtaz

Quantitative structure-activity relationship (QSAR) models were developed for the prediction of dermal absorption based on experimental log Kp data for a diverse set of 101 chemicals obtained from the literature. Molecular descriptors including topostructural (TS), topochemical (TC), shape or three-dimensional (3D) and …

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