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Federico Spataro, R. Ria, Mattia Cristallo, Lucia Indrio et autres
Not available
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Palma Carlucci, Marialuisa Sveva Marozzi, Francesco Corvasce, Silvia Noviello et autres
Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis characterized by eosinophilic inflammation and potential cardiovascular involvement. While pulmonary hypertension (PH) is uncommon, the relationship between eosinophil burden and subclinical pulmonary vascular dysfunction remains unclear. Methods: We conducted a single-centre …
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Federico Spataro, Fabio Cacciapaglia, Palma Carlucci, Antonio Giovanni Solimando et autres
No abstract available
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Federico Spataro, Antonio Giovanni Solimando, Vanessa Desantis, Angelo Vacca et autres
Lysosomal Storage Diseases (LSDs) encompass a range of genetic disorders characterized by enzyme deficiencies that lead to substrate accumulation and progressive tissue damage. Enzyme Replacement Therapy (ERT) is the primary treatment for LSDs, yet it is often associated with hypersensitivity reactions (HSRs), …
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Federico Spataro, Antonio Giovanni Solimando, Vanessa Desantis, Angelo Vacca et autres
BACKGROUND: Multiple myeloma (MM) is a malignancy characterized by the proliferation of abnormal plasma cells in the bone marrow, leading to osteolytic lesions. This condition is accompanied by a serum accumulation of monoclonal immunoglobulin. Zoledronic acid (ZA) is a new-generation bisphosphonate commonly …
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Federico Spataro, Roberto Ria, Nada Choul, Angelo Vacca et autres
INTRODUCTION: Acyclovir is a synthetic purine nucleoside analog that is used to treat infections caused by herpes simplex virus (HSV) and varicella zoster virus (VZV) by targeting the viral enzyme thymidine kinase. However, its use can lead to hypersensitivity reactions (HR) in …
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Federico Spataro, Roberto Ria, Nada Chaoul, Antonio Giovanni Solimando et autres
BACKGROUND: Mucopolysaccharidosis (MPS) type 1 S and type 2 are rare lysosomal storage disorders characterized by impaired enzyme production, resulting in glycosaminoglycans accumulation within lysosomes. Enzyme Replacement Therapy (ERT) with laronidase and idursulfase are first line treatments, respectively. However, infusion-related hypersensitivity reactions …
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Alessandro S. Massaro, Fabio Manca, Galiano Angelo, Assunta Melaccio et autres
Patrizia Leone, Mariangela Di Tacchio, Federico Perosa, Angelo Vacca et autres
Andréa Emília Marques Stinghen, Sandra Gonçalves, Sérgio Gardano Elias Bucharles, F.S. Branco et autres
Roberto Biassoni, Mario Ricci, Mariana Castells, Howard R. Katz et autres
William I. Rosenblum, Erik N.T.P. Bakker, Peter J.W. van der Linden, Pieter Sipkema et autres
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