Juan Carlos Kaski

Adherence to Guideline-Directed Medical Treatments in Heart Failure. A Scientific Statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Cardiovascular Pharmacotherapy

Gianluigi Savarese, Felix Lindberg, Antonio Cannatà, Marianna Adamo et autres

Heart failure (HF) affects over 60 million individuals globally. Contemporary guideline-directed medical therapies (GDMT) reduce cardiovascular mortality and HF hospitalizations. However, medication non-adherence represents a critical barrier limiting real-world efficacy of GDMT. This scientific statement aims to provide a comprehensive framework for …

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Therapies leading to coronary atherosclerosis plaque regression: a scientific statement of the European Association of Preventive Cardiology, the European Association of Cardiovascular Imaging of the ESC, the ESC Working Group on Atherosclerosis and Vascular Biology, and the ESC Working Group on Cardiovascular Pharmacotherapy Part 1: Atherosclerosis Pathophysiology and Imaging Evaluation

Edoardo Conte, Francesco Perone, Bernard Cosyns, Marc R. Dweck et autres

Coronary artery disease is one of the leading causes of mortality worldwide. While early identification and treatment of major cardiovascular risk factors are crucial, recent data suggest the possibility of non-invasively detecting early stages of coronary atherosclerosis and potentially stabilizing or even …

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European Journal of Heart Failure Consensus Statement. Heart Failure Pharmacotherapy for Patients with Heart Failure with Reduced Ejection Fraction and Concomitant Atrial Fibrillation: Review of Evidence and Call to Action

Mark Luedde, Stefan Agewall, Giuseppe Ambrosio, Antoni Bayés‐Genís et autres

Heart failure (HF) and atrial fibrillation (AF) are major global health challenges with rising prevalence and significant morbidity, mortality, and healthcare burden. Despite advances in HF management, AF remains a critical comorbidity that worsens outcomes and requires ad hoc treatment strategies, increasing …

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Management of dyslipidaemia in patients with comorbidities—facing the challenge: type 1 diabetes mellitus

Susanne Kaser, Dobromir Dobrev, Bianca Rocca, Juan Carlos Kaski et autres

Type 1 diabetes is associated with excess cardiovascular risk. In contrast to type 2 diabetes, however, age at the onset of type 1 diabetes and sex are major predictors of cardiovascular risk, while the role of low-density lipoprotein cholesterol (LDL-C) and lipid-lowering …

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Chronic coronary syndromes – guideline changes and a new nomenclature

Juan Carlos Kaski

Our understanding of the pathogenesis, clinical presentation, diagnosis, and management of angina pectoris has evolved substantially over the past few decades. Newer international guidelines have recently been published that provide recommendations for the diagnosis and management of ischaemic syndromes which are aligned …

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2024 EACTS Guidelines on perioperative medication in adult cardiac surgery

Anders Jeppsson, Bianca Rocca, Emma C. Hansson, Tómas Guðbjartsson et autres

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Management of dyslipidaemia in patients with comorbidities: facing the challenge

Gert Mayer, Dobromir Dobrev, Juan Carlos Kaski, Anne Grete Semb et autres

Dyslipidaemia is a common chronic kidney disease (CKD) and contributes to excessively elevated cardiovascular mortality. The pathophysiology is complex and modified by comorbidities like the presence/absence of proteinuria, diabetes mellitus or drug treatment. This paper provides an overview of currently available treatment …

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Preface by Juan Carlos Kaski

Juan Carlos Kaski

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Noise Pollution and Arterial Hypertension: Can we Remain Mute Anymore?

Sreenivasa Rao Kondapally Seshasai, Juan Carlos Kaski

Although the gains of the industrial revolution have transformed human life, they have also left an adverse impact on our health and environment.1 Therefore, factors such as environmental pollution (and pollutants) have lately been the subject of intense scientific investigation.

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Head and Neck Cancers: Why Is It Better to HPV than Not to HPV?

Paramita Baruah, Mike Lee, Phil Wilson, Juan Carlos Kaski et autres

Objectives: Dissect the impact of human papillomavirus (HPV) on angiogenesis in head and neck cancers (HNSCC). Methods: We analyzed 18 newly diagnosed HNSCC patients and controls. HPV tumor status was ascertained by p16 staining. Eleven pro‐ and anti‐angiogenic factors were quantified in …

Validation of a New Risk Score to Predict Contrast-Induced Nephropathy After Percutaneous Coronary Intervention

Dimitrios Tziakas, Georgios Chalikias, Dimitrios Stakos, Armağan Altun et autres

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A mutation in thioredoxin reductase 2 is associated with familial glucocorticoid deficiency

Rathi Prasad, Li F. Chan, Claire Hughes, Juan Carlos Kaski et autres