Elena Dogliotti

Promote Community Engagement in Participatory Research for Improving Breast Cancer Prevention: The P.I.N.K. Study Framework

Michela Franchini, Stefania Pieroni, Francesca Denoth, Marco Scalese et autres

Breast cancer (BC) has overtaken lung cancer as the most common cancer in the world and the projected incidence rates show a further increase. Early detection through population screening remains the cornerstone of BC control, but a progressive change from early diagnosis …

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Modulation of gut microbiota: The effects of a fruits and vegetables supplement

Arun Prasath Lakshmanan, Alessandra Mingione, Francesca Pivari, Elena Dogliotti et autres

The consumption of an optimal amount of fruits and vegetables is known to improve physical fitness and physiological body functions. Healthy eating habits, including intake of fruits and vegetables, can modify gut microbiota. This study aimed to demonstrate the effectiveness of a …

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Nutritional management of lactose intolerance: the importance of diet and food labelling

Maria Sole Facioni, Benedetta Raspini, Francesca Pivari, Elena Dogliotti et autres

Worldwide, 70% of the adult population has limited expression of lactase enzyme with a wide variation among different regions and countries. Lactase deficiency may lead to lactose intolerance (LI). Depending both on the amount of lactose ingested and on the lactase activity, …

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The benefits of nutritional counselling for improving sport performance

Laura Soldati, Francesca Pivari, Chiara Parodi, Caterina Brasacchio et autres

BACKGROUND: It is well known that the synergy between physical activity and healthy eating habits is an important combination for the achievement of different objectives. However, recent studies in the literature focused mainly on the effect of this synergy on weight loss …

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Aspetti epidemiologici della calcolosi di calcio in Italia: distribuzione dei fenotipi intermedi nella popolazione italiana

Teresa Arcidiacono, Francilene Nunes Rainone, Annalisa Terranegra, Elena Dogliotti et autres

Abstract non disponibile

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Interaction between polyphenols intake and PON1 gene variants on markers of cardiovascular disease: a nutrigenetic observational study

Federica Rizzi, Costanza Conti, Elena Dogliotti, Annalisa Terranegra et autres

BACKGROUND: Paraoxonase 1 (PON1) gene polymorphisms and polyphenols intake have been reported independently associated to lipid profile and susceptibility to atherosclerosis and cardiovascular disease. However, the interaction between these factors remains to be investigated. We performed an observational nutrigenetic study to examine …

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Nutritional and Genetic Determinants of Cardiovascular Risk

Annalisa Terranegra, Elena Dogliotti, Caterina Brasacchio, Costanza Conti et autres

A population of 503 adult Caucasians was recruited to evaluate the effect of diet on cardiovascular risk factors and its interaction with the genetic background. Nutritional data were collected by 24h recalls and Mediterranean diet adherence was investigated by QuADM-15 questionnaire. Anthropometric …

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Filamin A is Reduced and Contributes to CASR Sensitivity in Human Parathyroid Tumors

Annalisa Terranegra, Alessandra Mingione, Chiara Verdelli, Caterina Brasacchio et autres

Background Parathyroid tumors display reduced sensitivity to extracellular calcium ([Ca2+]o). The parathyroid cell sensitivity to [Ca2+]o is mediated by the calcium-sensing receptor (CASR), a G-protein-coupled receptor interacting with the scaffold protein filamin A (FLNA). We investigated: the FLNA expression in human parathyroid …

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Autosomal Dominant Hypocalcemia due to a Truncation in the C-Tail of the Calcium-Sensing Receptor

Annalisa Terranegra, Alessandra Mingione, Caterina Brasacchio, Katia Maruca et autres

Background Autosomal Dominant Hypocalcemia (ADH) is an endocrine disorder due to activating mutations of the calcium-sensing receptor (CASR) gene that encodes for a plasma membrane G protein-coupled receptor. This protein plays a central role in maintaining calcium homeostasis. ADH is characterized by …

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Calcium and Phosphate Intake May Influence Bone Remodeling Marker in Hemodialysis Patients

Annalisa Terranegra, Caterina Brasacchio, Alessandra Mingione, Elena Dogliotti et autres

Background Vascular calcification and increased mortality is now well linked in hemodialysis (HD) patients. Among the inhibitors and promoters of calcium-phosphate and bone metabolism, we studied Sclerostin, a glycoprotein mainly expressed by osteocytes, involved in regulating bone formation by inhibiting Wnt–β-catenin signaling. …

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Dietary style and acid load in an Italian population of calcium kidney stone formers

Giuseppe Vezzoli, Elena Dogliotti, Annalisa Terranegra, Teresa Arcidiacono et autres

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Risk of nephrolithiasis in primary hyperparathyroidism is associated with two polymorphisms of the calcium-sensing receptor gene

Giuseppe Vezzoli, Alfredo Scillitani, Sabrina Corbetta, Annalisa Terranegra et autres

AIMS: Two single-nucleotide polymorphisms (SNPs) at the calcium-sensing receptor (CASR) gene were previously associated with kidney stones in patients with primary hyperparathyroidism (PHPT): rs1501899, likely associated with a decrease in CASR expression, and Arg990Gly, causing a gain of CASR function. To evaluate …

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