Anabelle Brocard

Sirolimus for Secondary Prevention of Skin Cancer in Kidney Transplant Recipients: 5-Year Results

Jacques Dantal, Emmanuel Morélon, Lionel P. E. Rostaing, Eric Jean Goffin et autres

Purpose Transplant recipients who develop cutaneous squamous cell carcinomas are at high risk for multiple subsequent skin cancers. Sirolimus has been shown to reduce the occurrence of secondary skin cancers, but no study included a follow-up exceeding 2 years. We extended at …

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Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes in Advanced Melanoma Patients

Mélanie Saint-Jean, Anne‐Chantal Knol, Christelle Volteau, Gaelle Quereux et autres

Immunotherapy for melanoma includes adoptive cell therapy with autologous tumor-infiltrating lymphocytes (TILs). This monocenter retrospective study was undertaken to evaluate the efficacy and safety of this treatment of patients with advanced melanoma. All advanced melanoma patients treated with TILs using the same …

fr (code pays fourni par la source)

Severe dermatophytosis in solid organ transplant recipients: A French retrospective series and literature review

Claire Rouzaud, O. Chosidow, Anabelle Brocard, Sylvie Fraïtag et autres

OBJECTIVE: Severe dermatophytosis is described in immunocompromised patients with defective cellular immunity. We report here a large series and a literature review of severe dermatophytosis in solid-organ transplant (SOT) recipients. METHOD: The data main source was a national French retrospective study of …

fr, gb (code pays fourni par la source)

5-fluorouracil chemowraps for the treatment of multiple actinic keratoses

L. Peuvrel, Mélanie Saint-Jean, Gaelle Quereux, Anabelle Brocard et autres

Few satisfactory treatment options are available for widespread areas affected by multiple actinic keratoses (AKs). Our primary objective was to assess the response rate to weekly 5-fluorouracil (5-FU) chemowraps on widespread AK lesions, and secondarily to assess tolerability, the percentage of patients …

fr (code pays fourni par la source)

Risk of Aggressive Skin Cancers After Kidney Retransplantation in Patients With Previous Posttransplant Cutaneous Squamous Cell Carcinomas

Émilie Ducroux, Clemmie Martin, Jan Nico Bouwes Bavinck, Évelyne Decullier et autres

BACKGROUND: The course of skin cancer after retransplantation in organ-transplant recipients who have already developed posttransplant skin cancer has not been assessed. METHODS: This retrospective multicentric study included 53 patients with a history of cutaneous squamous cell carcinoma (SCC) after a first …

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Clinical, Genetic and Innate Immunity Characteristics of Melanoma in Organ Transplant Recipients

Anabelle Brocard, Anne‐Chantal Knol, Céline J. Bossard, Gaelle Quereux et autres

The aims of this study were to determine the clinical and histological characteristics of melanoma in transplant recipients, the mutation profile (BRAF, NRAS and c-KIT genes), and the immune tolerance of the tumour microenvironment by immunohistochemical study of the expression of indoleamine …

us, fr (code pays fourni par la source)

Intérêt des anti-CTLA4 et anti-PD1 dans les mélanomes vulvovaginaux inopérables ou métastatiques ?

Gaelle Quereux, Réjane Bouquin, Sophie Wylomanski, Mélanie Saint-Jean et autres

fr (code pays fourni par la source)

Toxican : un outil à d’aide à la cotation des toxicités cutanées des traitements anticancéreux au quotidien

L. Peuvrel, Julie Cassecuel, C. Bernier, A. Joubert et autres

fr (code pays fourni par la source)

Clinical significance of BRAF mutation status in circulating tumor DNA of metastatic melanoma patients at baseline

Anne Chantal Knol, Audrey Vallée, Guillaume Herbreteau, Jean‐Michel Nguyen et autres

Circulating tumor DNA is a promising non-invasive tool for cancer monitoring. The main objective of our work was to investigate the relationship between mutant BRAF DNA in plasma and clinical response. Thirty-eight stage IV patients with a V600 mutated BRAF melanoma were …

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KIDNEY RETRANSPLANTATION IN PATIENTS HAVING PRESENTED AT LEAST ONE SQUAMOUS CELL CARCINOMA DURING A PREVIOUS TRANSPLANTATION PERIOD EXPOSES TO A HIGH RISK OF AGGRESSIVE SKIN SQUAMOUS CELL CARCINOMA

Carmen San Martı́n, Jan Nico Bouwes Bavinck, Évelyne Decullier, Anabelle Brocard et autres

Dramatic response of an inoperable Merkel cell carcinoma with imatinib

Cécile Frénard, L. Peuvrel, Anabelle Brocard, Mélanie Saint-Jean et autres

Merkel cell carcinoma (MCC) is a rare type of skin tumor that is derived from epidermal neuroendocrine cells. It is an aggressive tumor for which the 5-year survival rate is estimated at 64% for localized tumors, 39% in cases of regional invasion, …

fr (code pays fourni par la source)

Détection de mutations de BRAF dans le plasma de patients atteints de mélanome métastatique

Anne‐Chantal Knol, Audrey Vallée, Émilie Varey, Jean Michel Nguyen et autres

fr (code pays fourni par la source)