Huanran Qu

Magneto‐Sono‐Enhanced Nanozyme Catalysis Drives ROS‐Mediated Pathogen Killing and Mitophagy‐Linked Inflammation Control in Bacterial Pneumonia

Xiaofeng Luo, Yundi Wu, Shuai Zhang, Huanran Qu et autres

ABSTRACT Bacterial pneumonia treatment faces significant challenges due to uncontrolled inflammation and rising antibiotic resistance. Excessive inflammatory cytokine release and mitochondrial dysfunction exacerbate tissue damage, contributing to the disease's progression. Mitophagy, a process that eliminates dysfunctional mitochondria, helps regulate reactive oxygen species …

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An "AND" Logic Gate S‐Scheme Nanozyme for Magneto‐Pyroelectric Dynamic Therapy Integrated With Lactate–Urate Immunometabolic Remodeling in Glioblastoma

Ruocan Liu, Yundi Wu, Shuai Zhang, Huanran Qu et autres

ABSTRACT Glioblastoma (GBM) therapy remains limited by poor blood–brain barrier (BBB) penetration and an adaptive, immunosuppressive tumor microenvironment (TME). Here, we engineer multifunctional FeWO x @Ag/Bi 2 Te 3 ‐HA nanozymes (FABH) to integrate magneto‐pyroelectric dynamic therapy (MPEDT), metabolic regulation, immune activation, …

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Micro/nanoplatforms for modulating programmed cell death and tumor inflammation

Xilong Wu, Huanran Qu, Yundi Wu

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Micro/nano-modulation of inflammatory signaling pathways in cancer

Xilong Wu, Yundi Wu, Cong Wang, Huanran Qu et autres

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List of contributors

Xilong Wu, Magda Chalecka, Xiangfeng Guan, Mowei Kong et autres

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Photo/Sono/Magneto‐Responsive Ternary Heteronanocrystals with S‐Scheme Heterojunction for Penetrative and ROS‐Amplified Tumor Ablation

Shuo Qiu, Yundi Wu, Ruocan Liu, Huanran Qu et autres

ABSTRACT Reactive oxygen species (ROS)‐based therapies are promising for tumor ablation, but their efficacy is limited by hypoxic microenvironments and poor intratumoral penetration. This study presents a photo/sono/magneto‐responsive ternary heteronanocrystal, BPNS/PCN‐224/Fe 3 O 4 @PVP (BPF), incorporating an S‐scheme heterojunction and Fe‐based …

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Engineering Lung-Adaptive Nanozymes for Drug-Resistant and Biofilm-Associated Bacterial Pneumonia

Shuai Zhang, Yundi Wu, Ruocan Liu, Huanran Qu et autres

Bacterial pneumonia represents a major global health burden, particularly in children, the elderly, and immunocompromised patients, and is increasingly complicated by multidrug-resistant pathogens and biofilm-protected infections. The central scientific problem is the imbalance between host defense and pathogen invasion, together with the …

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Plasmon-enhanced schottky nanoscaffolds for phototherapy and catalytic treatment of multidrug-resistant bacterial infections

Yundi Wu, Yingfei Wang, Huanran Qu, Xilong Wu

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Magnetothermal and ultrasound-activated nanoplatform for the inhalable therapy of bacterial lung infections

Shuai Zhang, Yang Wu, Huanran Qu, Xilong Wu

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Magnetically and optically powered nanozymes: Boosting breast cancer therapy with magnetothermodynamic-enhanced ferroptosis and apoptosis

Ruocan Liu, Yundi Wu, Huanran Qu, Xilong Wu

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NIR-II photo- and sono-responsive hyaluronic acid-capped nanozymes for glioblastoma-targeting theranostics

Huanran Qu, Yuanyuan Zhang, Minghao Chen, Shiyang Shao et autres

Glioblastoma is the most aggressive and heterogeneous astrocytic tumor, with its intracranial location limiting the efficacy of conventional therapies. This study presents the synthesis of a multifunctional nanocomplex utilizing borophene nanosheets (B NSs) as a substrate. Gold nanoparticles (Au NPs) are modified …

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