Yuyuan Lu

Ferroptosis regulation in doxorubicin-induced cardiotoxicity: multi-mechanism interventions and translational strategies

Xiaojie Chen, Yuyuan Lu, Yiyuan Wang, Yushun Kou et autres

Doxorubicin (DOX), a highly effective anthracycline chemotherapy drug, has its clinical application severely restricted by dose-dependent doxorubicin-induced cardiotoxicity (DIC). Ferroptosis, an iron-dependent, lipid peroxidation-driven regulated cell death, has been confirmed as a core pathological mechanism in DIC, where it synergistically participates with …

cn (code pays fourni par la source)

Prognostic Value of the Nutritional Risk Index and Hemoglobin-to-Platelet Ratio Score for Predicting Recurrence and Survival in Siewert II/III Gastroesophageal Junction Adenocarcinoma

Dianhong Lian, Zhen Yuan, Hao Cui, Bo Cao et autres

cn (code pays fourni par la source)

Mitochondrial dysfunction in hypertension: mechanistic pathways and therapeutic implications

Jiao Tian, Lin Yi, Yuyuan Lu, Yushun Kou et autres

cn (code pays fourni par la source)

Therapeutic efficacy and oncological prognosis of ypTNM 0-I gastric cancer after neoadjuvant therapy: a multicenter propensity-score matched study in China

Hao Cui, Yuyuan Lu, Huiguang Ren, Liqiang Song et autres

cn (code pays fourni par la source)

Gut Blautia coccoides-derived 5Z-dodecenoic acid attenuates chronic psychological stress-induced gastric cancer progression

Ruiyang Zhao, Yuyuan Lu, Qixuan Xu, Huiguang Ren et autres

BACKGROUND: Chronic psychological stress is a critical oncogenic factor of gastric cancer (GC). However, the mechanisms underlying stress-induced malignant progression remain largely unknown. Gut microbiota dysregulation is tightly associated with cancer development and metabolism. MATERIALS AND METHODS: Chronic unpredictable mild stress (CUMS) …

cn (code pays fourni par la source)

Regulated Cell Death and Inflammatory Signaling in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Strategies

Yuyuan Lu, Jia Cui, Xueyan Cheng, Jiawei Li et autres

cn (code pays fourni par la source)

Association of Copper with Atherosclerosis and Treatment Strategies

Jiawei Li, Yi Lin, Lingna Zhang, Lufan Shen et autres

cn (code pays fourni par la source)

Correlation between dyslipidaemia and gastric cancer: pathogenesis to prevention and treatment strategies

Tao Wu, Lingna Zhang, Jiao Tian, Yuyuan Lu et autres

As the sixth most common cancer in the world, the development of gastric cancer (GC) is influenced by many factors. Recent studies have revealed a strong association between dyslipidaemia and GC. In this paper, the relationships between dyslipidaemia and GC are discussed …

cn (code pays fourni par la source)

Pathologic complete response after Sintilimab combined with FOLFOX therapy in MSI-H type patients with locally advanced GC: a case report

Yuanhui Gu, Yi Lin, Tao Wu, Ling Wang et autres

As one of the most common gastrointestinal tumors, Gastric Cancer (GC) poses a serious threat to human health due to its high morbidity and mortality. The current treatment strategy is a comprehensive treatment program mainly based on surgery, especially for advanced GC …

cn (code pays fourni par la source)

The short-term efficacy of neoadjuvant SOX versus SOX plus immune checkpoint inhibitor following laparoscopic gastrectomy for locally advanced gastric cancer: a multicenter retrospective cohort study in China

Hao Cui, Yongpu Yang, Liqiang Song, Zhen Yuan et autres

BACKGROUND: This study aims to evaluate the short-term efficacy for locally advanced gastric cancer (LAGC) who accepted laparoscopic gastrectomy (LG) after neoadjuvant SOX versus SOX plus immune checkpoint inhibitors (ICIs). METHODS: LAGC patients who accepted LG after neoadjuvant SOX (SOX-LG, n = …

cn (code pays fourni par la source)