Esther Fernández Merino

Decitabine Conditioning Improves Natural Killer Cell Maturation and Limits CD8+ T Cell Terminal Differentiation Post-Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia Patients

Jesper van Eck van der Sluijs, Diede van Ens, A. M. Grotens, Esther Fernández Merino et autres

• Characterizing the NK and T cell immune landscape in AML patients post-alloSCT • Decitabine (DAC) conditioning improves NK cell maturation post-alloSCT • DAC conditioning limits CD8 + T cell terminal differentiation post-alloSCT • Donor NK/T cells from DAC conditioned patients remained …

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ATM and ATR inhibition increases radiosensitivity and cGAS-STING activation in prostate cancer

Nina van Campen, V. Mekers, Maaike W.G. Looman, Lune van den Bogaard et autres

Despite the availability of multiple effective therapies for localized prostate cancer, many patients still progress to incurable metastasized castration resistant prostate cancer (mCRPC). About 23 % of mCRPC patients carry alterations in DNA damage response (DDR) genes, including the protein kinases Ataxia …

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924: ATM and ATR inhibition increases radiosensitivity and may improve immunogenicity of prostate cancer.

Nina van Campen, Vera E. Mekers, Fabian Schuurmans, Esther Fernández Merino et autres