Maleeha Saqib

MPN-407: JAK Inhibitors vs Traditional Therapy for Myelofibrosis: A Meta-Analysis of Randomized Clinical Trials

Maleeha Saqib, Hassan Ijaz, Muhammad Musab Zubair, Nighat Shahbaz et autres

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JAK inhibitors vs traditional therapy for myelofibrosis; A meta-analysis of randomized clinical trials.

Maleeha Saqib, Hassan Ijaz, Muhammad Musab Zubair, Nighat Shahbaz et autres

e18603 Background: Myelofibrosis (MF) is a type of myeloproliferative neoplasm. The pharmacological standard of care is the Janus kinase (JAK) inhibitor class (e.g., Ruxolitinib, Pacritinib, Momelotinib, Fedratinib), which targets key disease drivers. However, traditional therapies, often grouped as Best Available Therapy (BAT), …

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Real-World Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia: A Single-Center Experience from a Low- and Middle-Income Country

Nighat Shahbaz, Saima Humayun Toor, Tariq Ghafoor, Maleeha Saqib et autres

Introduction Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the principal curative option for patients with high-risk or relapsed acute lymphoblastic leukemia (ALL), particularly in low- and middle-income countries (LMICs) where access to novel immunotherapies, including CAR-T cell therapy, remains limited. Real-world data …

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POSTER: MPN-946 A Systematic Review to Assess the Safety and Efficacy of Hydroxyurea and Pegylated Interferon in Myeloproliferative Neoplasms

Mahnoor Mahnoor, Salal Sharjeel, Roha Daneyal, Muhammad Bakhtiar et autres

MPN-946: A Systematic Review to Assess the Safety and Efficacy of Hydroxyurea and Pegylated Interferon in Myeloproliferative Neoplasms

Mahnoor Mahnoor, Salal Sharjeel, Roha Daneyal, Muhammad Bakhtiar et autres

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Navigating a Paradigm Shift Venetoclax Treatment Redefines Landscape of Acute Myeloid Leukemia

Muhammad Hamza Gul, Aisha Rehman Siddiqui, Farwa Zehra, Malaika Rehmani et autres

Acute myeloid leukemia (AML) is a heterogeneous disease characterized by the accumulation of malignant myeloid progenitor hematopoietic cells in the bone marrow and peripheral blood. Recent studies have shown promising results with the use of small molecule inhibitors and targeted therapy in …