M. B. Pereira

Origins and impact of extrachromosomal DNA

Chris Bailey, Oriol Pich, Kerstin Thol, Jens Luebeck et autres

. Here we examine the diversity of ecDNA elements across cancer, revealing the associated tissue, genetic and mutational contexts. By analysing data from 14,778 patients with 39 tumour types from the 100,000 Genomes Project, we demonstrate that 17.1% of tumour samples contain …

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Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme

Alona Sosinsky, John C. Ambrose, William Cross, Clare Turnbull et autres

The Cancer Programme of the 100,000 Genomes Project was an initiative to provide whole-genome sequencing (WGS) for patients with cancer, evaluating opportunities for precision cancer care within the UK National Healthcare System (NHS). Genomics England, alongside NHS England, analyzed WGS data from …

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Insights for precision healthcare from the 100,000 Genomes Cancer Programme

Nirupa Murugaesu, Alona Sosinsky, John C. Ambrose, William Cross et autres

Abstract The Cancer Programme of the 100,000 Genomes Project was a transformational UK government initiative that aimed to bring whole genome sequencing (WGS) to cancer patients and evaluate the opportunities for precision cancer care. Genomics England, in partnership with NHS England, generated …

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AN END-TO-END FRAMEWORK FOR LOW-RESOLUTION REMOTE SENSING SEMANTIC SEGMENTATION

M. B. Pereira

Abstract. High-resolution images for remote sensing applications are often not affordable or accessible, especially when in need of a wide temporal span of recordings. Given the easy access to low-resolution (LR) images from satellites, many remote sensing works rely on this type …

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Immediate progress and the probability of gene fixation in a method of selection.

M. B. Pereira