2024
article
OpenAlex
Wanghua Chen, Wenling Wang, Sicheng Huang, Lili Zhou et autres
OBJECTIVE: In this study, we retrospectively analysed the efficacy and safety of three treatment models, namely, short-course radiotherapy sequential XELOX chemotherapy, neoadjuvant mFOLFOX6 concurrent radiotherapy and long-course concurrent radiotherapy with total mesorectal excision (TME) after treatment of locally advanced rectal cancer with …
cn
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Accès ouvert
2024
article
OpenAlex
Yan Wang, Wenling Wang, Hongming Dong, Gang Wang et autres
Abstract Background and aims The cardiotoxicity related to 5-Fluorouracil (5-FU) in cancer patients has garnered widespread attention. The systemic immune-inflammation index (SII) has recently been identified as a novel predictive marker for the development of cardiovascular illnesses in individuals without pre-existing health …
cn
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Accès ouvert
2024
preprint
OpenAlex
Xiaoqin Liu, Yan Wang, Wenling Wang, Hongming Dong et autres
Abstract Background and aims: The cardiotoxicity related to 5-fluorouracil（5-FU） in cancer patients has garnered widespread attention. The systemic immune-inflammation index (SII) has recently been identified as a novel predictive marker for developing cardiovascular diseases in healthy individuals. However, it remains unclear whether …
cn
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Accès ouvert
2023
article
OpenAlex
Yan Wang, Wen‐Ling Wang, Hongming Dong, Gang Wang et autres
Background: Fluoropyrimidine is an important component of systemic chemotherapy for colorectal cancer (CRC). Fluoropyrimidine-induced cardiotoxicity (FIC) may result in delay and discontinuation of chemotherapy and, in severe cases, can even be life-threatening. To date, risk factors for FIC have not been well …
cn
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2022
conference-abstract
OpenAlex
Weiwei Chen, Hushan Zhang, Hongmin Dong, Gang Wang et autres
Abstract Background: Although the initial clinical results of immune checkpoint inhibitors (ICI) have been obtained in biliary tract cancer (BTC), and previous researches explored potential biomarkers for predicting response to ICI in BTC, and gene LRP1B was found as one of predictive …
cn
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Accès ouvert
2022
article
OpenAlex
Gang Wang, Wen‐Ling Wang, Haijie Jin, Hongmin Dong et autres
Background To effectively reduce the irradiated bowel volume so as to reduce intestinal toxicity from pelvic radiotherapy, treatment in the prone position with a full bladder on a belly board is widely used in pelvic radiotherapy for rectal cancer patients. However, the …
cn
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Accès ouvert
2022
article
OpenAlex
Hui Wang, Chunhui Chen, Da Chen, Fengsheng Li et autres
PURPOSE: To summarize the technical points and clinical effects of percutaneous balloon compression (PBC) in the treatment of primary trigeminal neuralgia. METHODS: The clinical data of 13 patients with trigeminal neuralgia who received PBC from April 2020 to July 2021 were retrospectively …
cn
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Accès ouvert
2020
article
OpenAlex
Sai-Xi Bai, Ruo-rong Zhang, Wanghua Chen, Hongmin Dong et autres
Objective To compare the clinical efficacy and safety of nimotuzumab combined with chemotherapy versus chemotherapy alone as first-line treatment for advanced colorectal cancer (ACRC). Method We retrospectively enrolled patients with ACRC treated with nimotuzumab plus chemotherapy (n = 40) or chemotherapy alone …
cn
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2019
conference-abstract
OpenAlex
Sai-Xi Bai, Ruo-rong Zhang, Wanghua Chen, Hongmin Dong et autres
e15009 Background: To retrospectively analyze the clinical effects and safety of nimotuzumab combined with chemotherapy as the first-line treatment of advanced colorectal cancer (ACRC). Methods: ACRC patients treated by nimotuzumab combined with chemotherapy (40 cases) or chemotherapy alone (44 cases) were enrolled …
cn
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Accès ouvert
2018
article
OpenAlex
Wanghua Chen, Wen‐Ling Wang, Yuxin Li, Hongmin Dong et autres
BACKGROUND: To investigate the efficacy and safety of concurrent chemoradiotherapy with capecitabine or oxaliplatin in locally advanced (T3-4/N + M0) rectal cancer. METHODS: 56 patients with rectal cancer after radical operation were randomly divided into CAPE-OX-CRT group: capecitabine + oxaliplatin concurrent chemoradiotherapy …
cn
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