Accès ouvert
2025
article
OpenAlex
Pierre Seners, Nour Nehme, Adrien ter Schiphorst, Frédérique Charbonneau et autres
Importance: In patients with acute ischemic stroke due to large vessel occlusion (AIS-LVO), the benefit of intravenous thrombolysis (IVT) administered beyond 4.5 hours from the last time known well before endovascular therapy (EVT) is uncertain. Recently, the TIMELESS trial failed to demonstrate …
fr, lb, us, Afrique du Sud
(code pays fourni par la source)
2025
article
OpenAlex
Simon Liebart, Maarten G. Lansberg, Grace Adwane, Frédérique Charbonneau et autres
Background and ObjectivesThe benefit of IV thrombolysis (IVT) before endovascular therapy (EVT) in acute ischemic stroke patients with basilar artery occlusion (BAO) remains unclear. Most existing studies have focused on patients directly admitted to comprehensive stroke centers (CSCs), where EVT is readily …
fr, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Maria Fahmy, Vincent Brissette, Danielle Carole Roy, Joyce Beshara et autres
ABSTRACT Background and aims: Achieving a first pass recanalization (FPR) improves clinical outcomes in patients with basilar artery strokes, but its association with initial infarct burden is unknown. We aimed to study the benefits of FPR for basilar artery strokes by initial …
ca, fr, jp
(code pays fourni par la source)
2025
article
OpenAlex
Mikaël Mazighi, Jérôme Lambert, Benjamin Gory, Pierre Seners et autres
BACKGROUND: Glenzocimab is a humanized fragment of a monoclonal antibody directed against the human platelet glycoprotein VI, which has shown promising features, including thrombus growth inhibition and minimal bleeding risk. The first inpatient study suggested the benefit of glenzocimab with alteplase in …
fr, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Marion Yger, Édouard Januel, Thomas Checkouri, Nicolas Chausson et autres
INTRODUCTION: A better understanding of sex-related differences remains key to improve stroke care for women. We aimed to assess the differences of prognosis, symptomatic intracranial hemorrhage (sICH) rates and process times between men and women suffering from ischemic stroke. PATIENTS AND METHODS: …
fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Naëiri Pauillac, Dorothée Faille, Mialitiana Solo Nomenjanahary, Mélanie Souvanheuane et autres
BACKGROUND: Hemorrhagic transformation (HT) frequently occurs in acute ischemic stroke patients with a large vessel occlusion undergoing endovascular therapy (EVT), significantly impacting functional outcomes. We aimed to determine whether an early fibrinogen depletion coagulopathy (FDC) was associated with HT following bridging therapy …
fr, be
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
William Boisseau, Augustin Lecler, Stanislas Smajda, Pierre Seners et autres
INTRODUCTION: Computed Tomography (CT) is the main modality used for the diagnosis and classification of hemorrhagic transformation (HT) after thrombectomy, however its reliability has shown limitations. Dual-energy CT (DECT) and magnetic resonance imaging (MRI) have been suggested to enhance the reliability of …
fr, ca
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
João Pedro Marto, Davide Strambo, George Ntaios, Thanh N. Nguyen et autres
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with an increased risk of cerebrovascular and other thrombotic events. 1 Previous studies have shown that patients with acute ischemic stroke (AIS) and coronavirus disease 2019 (COVID-19) have a worse functional outcome …
pt, ch, gr, us, pl, fr, it, Égypte, es, ro, nl, cz, be, de
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Cyril Dargazanli, Isabelle Mourand, Mehdi Mahmoudi, Luc Poirier et autres
Abstract Background: Patients with acute basilar artery occlusion (BAO) and low-to-moderate symptoms (National Institutes of Health Stroke Scale [NIHSS] < 10) are poorly represented in thrombectomy trials. Our objective is to compare thrombectomy and best medical management (BMT) in this population. Methods: …
fr, ca, us, be
(code pays fourni par la source)
2021
article
OpenAlex
François Delvoye, Stéphane Loyau, Julien Labreuche, Guillaume Taylor et autres
Background – Immediate reocclusion after mechanical thrombectomy (MT) for acute ischemic stroke (AIS) is a rare but devastating condition associated with poor functional outcome.Objective – The aim of this study was to gain insights into the mechanisms underlying immediate reocclusion, and to …
be, fr
(code pays fourni par la source)