A. Spötter

Genome-Wide Association Study of aVarroa-Specific Defense Behavior in Honeybees (Apis mellifera)

A. Spötter, Pooja Gupta, M. Mayer, N. Reinsch et autres

Honey bees are exposed to many damaging pathogens and parasites. The most devastating is Varroa destructor, which mainly affects the brood. A promising approach for preventing its spread is to breed Varroa-resistant honey bees. One trait that has been shown to provide …

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A new approach for honeybee breeding - genomic selection

Kaspar Bienefeld, A. Spötter, N. Reinsch, Manfred Mayer et autres

Accuracy of the unified approach in maternally influenced traits - illustrated by a simulation study in the honey bee (Apis mellifera)

Pooja Gupta, N. Reinsch, A. Spötter, Tim Conrad et autres

BACKGROUND: The honey bee is an economically important species. With a rapid decline of the honey bee population, it is necessary to implement an improved genetic evaluation methodology. In this study, we investigated the applicability of the unified approach and its impact …

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Simulating a base population in honey bee for molecular genetic studies

Pooja Gupta, Tim Conrad, A. Spötter, N. Reinsch et autres

BACKGROUND: Over the past years, reports have indicated that honey bee populations are declining and that infestation by an ecto-parasitic mite (Varroa destructor) is one of the main causes. Selective breeding of resistant bees can help to prevent losses due to the …

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Development of a 44K SNP assay focussing on the analysis of a varroa‐specific defence behaviour in honey bees (Apis mellifera carnica)

A. Spötter, Pooja Gupta, Gerd Nürnberg, N. Reinsch et autres

Honey bees are exposed to a number of damaging pathogens and parasites. The most destructive among them, affecting mainly the brood, is Varroa destructor. A promising approach to prevent its spread is to breed for Varroa-tolerant honey bees. A trait that has …

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Restriction of Porcine Endogenous Retrovirus by Porcine APOBEC3 Cytidine Deaminases

Eva Dörrschuck, Nicole Fischer, Ignacio G. Bravo, Kay-Martin Hanschmann et autres

Xenotransplantation of porcine cells, tissues, and organs shows promise to surmount the shortage of human donor materials. Among the barriers to pig-to-human xenotransplantation are porcine endogenous retroviruses (PERV) since functional representatives of the two polytropic classes, PERV-A and PERV-B, are able to …

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Development of a SNP-Assay for varroa tolerance in the honey bee.

A. Spötter, Pooja Gupta, N. Reinsch, Fred Zautke et autres

Whole‐genome scan for guttural pouch tympany in Arabian and German warmblood horses

Alexandra Zeitz, A. Spötter, I. Blazyczek, Ulrike S. Diesterbeck et autres

Equine guttural pouch tympany (GPT) is a hereditary disease in foals of several breeds, including thoroughbreds, Arabian, Quarter and warmblood horses. We performed a whole-genome scan for GPT in 143 horses from five Arabian and five German warmblood families and genotyped 257 …

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Effect of Polymorphisms in Four Candidate Genes for Fertility on Litter Size in a German Pig Line

A. Spötter, H. Hamann, Sandra Müller, O. Distl

We carried out an SNP discovery project in pigs for candidate genes playing potentially important roles in embryonic development. Using eight pigs one each from eight breeds (Meishan, Mangalitza, Duroc, Pietrain, German Landrace, Hampshire, Husum Red Pied, German Large White), 36 SNPs …

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Effect of Polymorphisms in the Genes for LIF and RBP4 on Litter Size in Two German Pig Lines

A. Spötter, Sandra Müller, H. Hamann, O. Distl

Contents The association of two diallelic polymorphisms in the porcine genes for leukaemia inhibitory factor (LIF) and retinol‐binding protein 4 (RBP4) with number of piglets born alive (NBA) in two German pig lines was studied. The investigated single nucleotide polymorphism (SNP) in …

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An insertion/deletion in the porcine FGFR2 gene

J. Aldenhoven, A. Spötter, O. Distl

The 7000-rad INRA-University of Minnesota porcine Radiation Hybrid panel was used to localize the FGFR2 gene on Sus scrofa chromosome 14 (SSC14). An insertion/deletion mutation of approximately 240 bp was detected in the porcine FGFR2 gene. This mutation consists of a repeat …

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Genetic approaches to the improvement of fertility traits in the pig

A. Spötter, O. Distl

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