Accès ouvert
2025
article
OpenAlex
Xiaolong Lu, Qiwen Zhou, Mingzhu Wang, Meiqi Li et autres
Newcastle disease virus (NDV), a widespread poultry pathogen, spreads efficiently via the respiratory tract. However, the precise mechanism governing its spreading infection remains unclear. This study reveals that NDV-induced tight junction (TJ) injury is crucial for viral replication and spread. NDV infection …
cn
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Accès ouvert
2024
article
OpenAlex
Dongchang He, Xiyue Wang, Huiguang Wu, Kairui Cai et autres
Vaccination is crucial for the prevention and mitigation of avian influenza infections in China. The inactivated H7N9 vaccine, when administered to poultry, significantly lowers the risk of infection among both poultry and humans, while also markedly decreasing the prevalence of H7N9 detections. …
cn
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Accès ouvert
2024
article
OpenAlex
Xiaoquan Wang, Xinen Tang, Huafen Zheng, Ruyi Gao et autres
H7N9 subtype avian influenza viruses (AIVs) cause 1567 human infections and have high mortality, posing a significant threat to public health. Previously, we reported that two avian-derived H7N9 isolates (A/chicken/Eastern China/JTC4/2013 and A/chicken/Eastern China/JTC11/2013) exhibit different pathogenicities in mice. To understand the …
cn, mv
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Accès ouvert
2017
article
OpenAlex
Jingjing Liu, Jie Zhu, Haixu Xu, Juan Li et autres
Newcastle disease (ND) leading to heavy economic losses to the poultry industry worldwide is caused by Newcastle disease virus (NDV). Even though intensive vaccination programs have been implemented in many countries, virulent NDV can still be frequently isolated in well-vaccinated flocks. We …
cn
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