J R Westphal

Primary ureteroscopy with a 6.3 Fr single-use flexible ureteroscope: Feasibility and safety in first clinical experience

Benedikt Ebner, J R Westphal, I. Papadopoulos, T. Georgieva et autres

A preliminary study on a new model system to evaluate tumour-detection and tumour-purging protocols in ovarian cortex tissue intended for fertility preservation

Ronald Peek, L. Bastings, J R Westphal, Leon F.A.G. Massuger et autres

STUDY QUESTION: Is it possible to create a model system that mimics ovarian metastatic disease in order to devise new strategies to detect cancer cells and prevent cancer cell transmission via ovarian tissue autotransplantation in cancer survivors? SUMMARY ANSWER: Injection of bovine …

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Efficacy of ovarian tissue cryopreservation in a major European center

L. Bastings, Jana Liebenthron, J R Westphal, C. C. M. Beerendonk et autres

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Plasminogen activators are involved in angiostatin generation in vivo in benign and malignant ovarian tumor cyst fluids

Angela A.G. van Tilborg, Fred C.G.J. Sweep, Anneke Geurts‐Moespot, A.M.M. Wetzels et autres

In many tumor types, angiogenesis is the net result of pro- and anti-angiogenic mediators and correlated with metabolic activity, growth, and degree of malignancy. One of the first discovered anti-angiogenic compounds is angiostatin, a proteolytic fragment of plasminogen. The requirements for in …

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Autotransplantation of cryopreserved ovarian tissue in cancer survivors and the risk of reintroducing malignancy: a systematic review

L. Bastings, C. C. M. Beerendonk, J R Westphal, Leon F.A.G. Massuger et autres

BACKGROUND The risk of recurrent oncological disease due to the reintroduction of cancer cells via autotransplantation of cryopreserved ovarian tissue is unknown. METHODS A systematic review of literature derived from MEDLINE, EMBASE and the Cochrane Library was conducted. Studies on follow-up after …

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Fertility Preservation for Pre-Pubertal Girls and Young Female Cancer Patients

R. Gerritse, L. Bastings, C. C. M. Beerendonk, J R Westphal et autres

New protocols in the early diagnosis and treatment of cancer have led to major improvements in the long-term survival of patients. However, aggressive chemotherapy or radiotherapy of the pelvic region, often lead to infertility, due to the damage of the follicles and/or …

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Fertility preservation in young patients before allogeneic haematopoietic SCT

L. Bastings, J R Westphal, C. C. M. Beerendonk, D.D.M. Braat et autres

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Glucose/lactate metabolism of cryopreserved intact bovine ovaries as a novel quantitative marker to assess tissue cryodamage

R. Gerritse, C. C. M. Beerendonk, J R Westphal, L. Bastings et autres

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POSTER VIEWING SESSION - ANDROLOGY

E. C. Dul, Conny M.A. van Ravenswaaij‐Arts, Henk Groen, J Van Echten-Arends et autres

POSTER VIEWING SESSION - MALE AND FEMALE FERTILITY PRESERVATION

N. Akakubo, N. Kagawa, Akiko Yabuuchi, Sherman J. Silber et autres

In vitro 17ß-oestradiol release as a marker for follicular survival in cryopreserved intact bovine ovaries.

R. Gerritse, Ronald Peek, Fred C.G.J. Sweep, C. Thomas et autres

Transplantation of cryopreserved intact ovaries from cancer patients is a technically challenging option for restoring fertility after sterilizing cancer therapy. In this paper we describe an assay based on 17ß-oestradiol (oestradiol) production, to monitor the functional damage sustained by the ovarian tissue …

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Optimal perfusion of an intact ovary as a prerequisite for successful ovarian cryopreservation

R. Gerritse, C. C. M. Beerendonk, M.S.L. Tijink, A. Heetkamp et autres

BACKGROUND: Cryopreservation and subsequent reimplantation of intact ovaries from cancer patients, offers potentially the best prognosis for restoring fertility after sterilizing cancer treatment. We used bovine ovaries as a model system to explore the perfusion procedure that is required for cryopreservation of …

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