Jordan J. Feld

3PC-032 Promoting the role of hospital pharmacists in cancer care: patients’ perspectives on the chemotherapy preparation process and information tools

Jérome Convert, S Soetaert, A Nabati, LK El Hassani et autres

Background and Importance The preparation of injectable chemotherapy drugs, although crucial to treatment safety, often remains poorly understood by patients. To improve transparency and promote the role of hospital pharmacists, an information leaflet describing the activities of the Unit for Preparation and …

fr (code pays fourni par la source)

The 14th Canadian Symposium on Hepatitis C Virus: From research breakthroughs to equitable health care for priority populations

Elakpa Daniel Ngbede, David Lawton, Trinity H. Tooley, Kerryn van Rooyen et autres

Background: The hepatitis C virus (HCV) affects approximately 214,000 Canadians. While the availability of safe, effective direct-acting antivirals (DAA) has led to decreased rates of chronic HCV infection and increased treatment uptake, major challenges to achieving HCV elimination remain. This report summarizes …

ca, au (code pays fourni par la source)

Association Between Sustained Virological Response and Adverse Liver-Related Events in Patients With Decompensated Hepatitis C Virus Cirrhosis

Lisa M. van Velsen, Lisette Krassenburg, Grishma Hirode, Kosh Agarwal et autres

BACKGROUND & AIMS: Sustained virological response (SVR) improves prognosis in patients with chronic hepatitis C virus (HCV) with compensated cirrhosis, but whether a similar benefit can be obtained in decompensated patients is controversial. We studied the association between SVR and liver-related events …

nl, ca, gb, de, es, it (code pays fourni par la source)

WED-264 Glecaprevir/pibrentasvir in chronic HCV: an integrated analysis of patients on concomitant opioids, antipsychotics and cardiovascular medications

Curtis Cooper, Lisa W. Johnson, Jordan J. Feld, Ashley Brown et autres

TOP-266 Association between sustained virological response and adverse liver-related outcomes in patients with decompensated HCV cirrhosis

Lisa M. van Velsen, Lisette Krassenburg, Grishma Hirode, Kosh Agarwal et autres

Getting to HBV cure—Will new biomarkers help?

Jordan J. Feld, Adam J. Gehring, Fabien Zoulim

The natural history and response to therapy in chronic hepatitis B (CHB) infection have been defined by a combination of serological and virological biomarkers along with liver biochemistry and/or histology. A number of novel biomarkers, including HBV RNA, hepatitis B core-related antigen, …

ca, fr, us (code pays fourni par la source)

Health Utilities in People with Hepatitis C Virus Infection: A Study Using Real-World Population-Level Data

Yasmin Saeed, Nicholas Mitsakakis, Jordan J. Feld, Murray Krahn et autres

BackgroundHepatitis C virus (HCV) infection is associated with reduced quality of life and health utility. It is unclear whether this is primarily due to HCV infection itself or commonly co-occurring patient characteristics such as low income and mental health issues. This study …

ca (code pays fourni par la source)

Clinical- and Cost-Effectiveness of Liver Disease Staging in Hepatitis C Virus Infection: A Microsimulation Study

Rachel Epstein, Sarah Munroe, Lynn E. Taylor, Patrick Duryea et autres

BACKGROUND: Liver disease assessment is a key aspect of chronic hepatitis C virus (HCV) infection pre-treatment evaluation but guidelines differ on the optimal testing modality given trade-offs in availability and accuracy. We compared clinical outcomes and cost-effectiveness of common fibrosis staging strategies. …

us, ca, fr (code pays fourni par la source)

Mixed‐Genotype HCV Direct Acting Antiviral Outcomes: A CANUHC Analysis

Haris Imsirovic, Gisela Macphail, Brian E. Conway, Chris Fraser et autres

The prevalence of mixed hepatitis C virus (HCV) genotype infection in a representative Canadian HCV cohort is reported and virological response with direct acting antiviral (DAA) treatment was evaluated. 3272 HCV-positive participants were enrolled, of which 2945 (90.0%) initiated DAA therapy. 0.8% …

ca (code pays fourni par la source)

Liver disease symptoms are associated with higher risk of adverse clinical outcomes: A longitudinal study of North American adults with chronic Hepatitis B

Donna M. Evon, Hsing‐Hua Sylvia Lin, Robert J. Fontana, Mandana Khalili et autres

BACKGROUND: Symptoms of chronic hepatitis B (CHB) are not well characterized. AIMS: To evaluate CHB symptoms and associations with disease activity and clinical outcomes. METHODS: Longitudinal data from 1,576 participants in the Hepatitis B Research Network Cohort Study who completed symptom assessments …

us, ca (code pays fourni par la source)

Simplified monitoring for hepatitis C virus treatment with glecaprevir plus pibrentasvir, a randomised non-inferiority trial

Gregory J. Dore, Jordan J. Feld, Alex Thompson, Marianne Martinello et autres

au, ca, us, gb, ch, de, fr, nz (code pays fourni par la source)

PS-178-Simplified monitoring for hepatitis C virus treatment with glecaprevir plus pibrentasvir: the SMART-C study

Gregory J. Dore, Jordan J. Feld, Alexander Thompson, Marianne Martinello et autres