T. Hoshino

The Effect of Maturation on Insulin Secretion after Starvation in Isolated Perfused Rat Pancreas

T. Ikeda, T. Hoshino, Masashi Honda, T. Takeuchi et autres

To determine the effect of maturation on glucose-induced insulin release after starvation, we investigated the insulin release from perfused pancreas of young adult rats after fasting for 18-20 hr. In the rats weighing 300-400 g (12-14 w) and 200-250 g (7-8 w), …

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Effect of Long-term Administration of Insulin and Glibenclamide on Pancreatic A and B Cell Function

Takuya Ikeda, K. Fujiyama, T. Hoshino, T. Takeuchi et autres

To investigate the effects of insulin and sulfonylurea drug administration on islet A and B-cell functions, insulin and glucagon response was studied in normal rats treated with insulin (4 U/day subcutaneously) or glibenclamide (0.03 mg/kg intraperitoneally) for 8 weeks. In intravenous glucose …

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Adrenergic Mechanism in Hyperketonemia in Thyrotoxic and Starved Rats

T. Ikeda, Hiroshi Ochi, Izumi Ohtani, K. Fujiyama et autres

To evaluate the possible role of the adrenergic mechanism in hyperketonemia in hyperthyroidism and starvation, the plasma concentrations of FFA, acetoacetate (AcAc), and beta-hydroxybutyrate (BOHB) were measured in thyrotoxic and starved rats for 96 hours. Thyrotoxemia was induced in rats by a …

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Inhibitory Effect of Fatty Acids on Glucose and Insulin Uptake in the Perfused Rat Hindquarter

T. Ikeda, Hikari Terasawa, Masahiko Ishimura, Hiroshi Ochi et autres

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Effects of 1?-hydroxyvitamin D3 on lumbar bone mineral density and vertebral fractures in patients with postmenopausal osteoporosis

Hajime Orimo, Masataka Shiraki, Yujiro Hayashi, T. Hoshino et autres

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The Importance of the Host Nutritional and Immune Status on the Prognosis of Urinary Tract Infection in the Elderly.

Kenji Toba, Noriko Sudoh, Yasuyoshi Ouchi, J.-M. Lien et autres

This study was performed to evaluate the role of the nutritional and immune status on the prognosis of urinary tract infections (UTI) in the elderly. 192 patients among the 790 inpatients were diagnosed as UTI. Age-related increase in the prevalence of UTI …

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In Vitro Effects of Glycosylated Insulin and Glucagon in Perfused Liver of the Rat

Tatsunori Ikeda, Hiroshi Ochi, Izumi Ohtani, K. Fujiyama et autres

Using perfused liver of the rat, the hepatic uptake of glycosylated insulin (GI) and glucagon (GG) and its effects on hepatic glucose output were investigated. Insulin and glucagon were glycosylated in ambient high glucose concentration, and GI80 or GG80 (insulin or glucagon …

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Serum lipid and apolipoprotein levels in non‐hypertensive lean NIDDM patients

T. Ikeda, Hiroshi Ochi, Izumi Ohtani, K. Fujiyama et autres

To determine the possible role of a glycaemic control in lipid metabolism in non-insulin-dependent diabetes mellitus (NIDDM) patients, serum lipid and apolipoprotein levels were measured in well-controlled and poorly controlled lean NIDDM without proteinuria and hypertension. A sample of 96 lean NIDDM …

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Possible role of adrenergic mechanism in starvation-induced reduction in circulating thyroxine and triiodothyronine in rats

Tadasu Ikeda, Izumi Ohtani, T. Hoshino, Yasushi Tanaka et autres

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Stimulating effect of thyroid hormone on insulin-like growth factor I release and synthesis by perfused rat liver.

T. Ikeda, K. Fujiyama, T. Hoshino, Yuukichi Tanaka et autres

The direct effect of thyroid hormone on insulin-like growth factor I (IGF-I) release and synthesis was investigated in perfused rat liver. Physiological doses (from 50 to 1000 ng/dl) of 3,5,3'-triiodothyronine administration in the perfusing medium increased IGF-I release and concentration in the …

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[Effect of eel calcitonin derivative (elcatonin) in osteoporosis].

S Yoshikawa, Masayuki Shiba, T. Hoshino, 睦夫 五十嵐 et autres

Calcitonin has been considered to be useful in the treatment of osteoporosis due to its remarkable suppressive action on bone resorption as well as its putative stimulative effect on bone formation. However, its usefullness, especially the effect for decreasing the loss of …

[Serial change in urinary protein electrophoresis based on molecular size difference in acute glomerulonephritis].

Kan K, M Izeki, T. Hoshino, Kyoko Konishi et autres