Steven E. Goldberg

Cost and Utilization Outcomes of Pharmacist-Led Medication Therapy Optimization in a Medicare ACO Population

Hazem Fathy Elewa, Joseph F Levy, Chintan J. Pandya, Steven E. Goldberg et autres

Abstract Introduction Medication-related problems are a persistent source of avoidable spending among Medicare beneficiaries, presenting an important opportunity to improve the quality of care for seniors and reduce financial burden on the Medicare program. Methods We evaluated a pharmacist-led medication therapy optimization …

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Diagnostics and Decisions: Molecular Test Insights in Shared Decision-Making for Managing Respiratory Infections

Zachary N. Goldberg, Maren Susan Fragala, Azia S. Evans, Steven E. Goldberg

Unlabelled: Advancements in diagnostic technologies for the evaluation of infectious disease complaints in the outpatient setting have improved the speed and accuracy of pathogen detection and created the opportunity for higher accuracy in treatment planning. The benefits of these advanced diagnostics insights …

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Health Care Utilization and Cost of Diagnostic Testing for Respiratory Infections

Azia S. Evans, Riddhi Doshi, Jason Yeaw, Katharine B. Coyle et autres

OBJECTIVES: This study compared all-cause health care resource use (HCRU) and costs between patients with acute oropharyngeal infections and respiratory tract infections (RTIs) receiving targeted syndromic real-time polymerase chain reaction (RT-PCR) tests with next-day results vs matched patients receiving other/no diagnostic tests. …

Diagnostics and Decisions: Molecular Test Insights in Shared Decision Making for Managing Respiratory Infections (Preprint)

Zachary N. Goldberg, Maren Susan Fragala, Azia S. Evans, Steven E. Goldberg

UNSTRUCTURED Advancements in diagnostic technologies for the evaluation of infectious disease complaints in the outpatient setting have improved the speed and accuracy of pathogen detection and created the opportunity for higher accuracy in treatment planning. The benefits of these advanced diagnostics insights …

Is Pathogen Molecular Testing Reshaping Outpatient Antibiotic Prescribing?

Barbara Dudley Alexander, William D Irish, Adriana E. Rosato, Barry I. Eisenstein et autres

Timely microbiological diagnosis is necessary to optimize treatments, improve antimicrobial stewardship, and improve patient and population health outcomes. For example, in a recent randomized clinical trial of hospitalized patients with community-acquired pneumonia, the use of syndromic polymerase chain reaction (PCR)-based diagnostic test …

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Utilization of Syndromic Vaginitis Diagnostic Testing Reduces 6-Month Follow-Up Outpatient Service Healthcare Costs—A Real-World Data Analysis

Azia S. Evans, Maren Susan Fragala, Pallavi Upadhyay, Andrea J. French et autres

Background/Objectives: Vaginitis is a common infection among women of reproductive age. Although various diagnostic methodologies exist, diagnosis without the utilization of available diagnostic tests remains prevalent. This study aimed to assess downstream healthcare utilization and the cost of patients with and without …

Clinical and economic outcomes of a pharmacogenomics-enriched comprehensive medication management program in a self-insured employee population

Maren Susan Fragala, Murray Keogh, Steven E. Goldberg, Raymond A. Lorenz et autres

Clinical and economic outcomes from a pharmacogenomics-enriched comprehensive medication management program were evaluated over 26 months in a self-insured U.S. employee population (n = 452 participants; n = 1500 controls) using propensity matched pre-post design with adjusted negative binomial and linear regression …

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Molecular Testing for Women’s Gynecologic Health: Real-World Impact on Health Care Costs

Azia S. Evans, Maren Susan Fragala, Pallavi Upadhyay, Andrea French et autres

Molecular Testing for Respiratory Tract Infections May Have Favorable Impact on Real-world Healthcare Costs

Azia S. Evans, Vijay Singh, Pallavi Upadhyay, Maren Susan Fragala et autres

Molecular testing by Polymerase Chain Reaction (PCR) has improved diagnostic performance to inform appropriate treatment. However, its impact on healthcare utilization and costs related to respiratory tract infections are yet to be studied in detail. The aim of this study is to …

Prediction of Future Medical Costs by Modifiable Measures of Health

Farnoosh Haji‐Sheikhi, Maren Susan Fragala, Lance A. Bare, Charles M. Rowland et autres

Introduction: Strategies to mitigate rising health-care costs are a priority for patients, employers, and health insurers. Yet gaps currently exist in whether health risk assessment can forecast medical claims costs. This study examined the ability of a health quotient (HQ) based on …

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Role of Pharmacogenomics in Comprehensive Medication Management: Considerations for Employers

Maren Susan Fragala, Jeffrey A. Shaman, Raymond A. Lorenz, Steven E. Goldberg

Rising prescription costs, poor medication adherence, and safety issues pose persistent challenges to employer-sponsored health care plans and their beneficiaries. Comprehensive medication management (CMM), a patient-centered approach to medication optimization, enriched by pharmacogenomics (PGx), has been shown to improve the efficacy and …

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Early Insights From a Pharmacogenomic-Enriched Comprehensive Medication Management Program Implementation in an Adult Employee Population

Murray Keogh, Maren Susan Fragala, Arul Prakasam Peter, Raymond A. Lorenz et autres

OBJECTIVES: The aims of the study are to assess adoption of a pharmacogenomic-enriched comprehensive medication management program in a self-insured employer setting and to better understand medication risks that affect employees. METHODS: Employees were identified to be at high risk of medication …